Venoarterial Carbon Dioxide Gradient and Central Venous Oxygen Saturation as a Prognostic Value in Severe Intraabdominal Sepsis | ||||
| The Egyptian Journal of Hospital Medicine | ||||
| Article 96, Volume 93, Issue 1, October 2023, Page 7535-7540 PDF (391.02 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/ejhm.2023.326650 | ||||
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| Abstract | ||||
| Background: For physicians, the prognostic value of central venous oxygen saturation (ScvO2) and venoarterial carbon dioxide difference (PvaCO2) among severe sepsis patients remains unclear. Objective: The aim of this study was for assessment of the prognostic value of PvaCO2 and ScvO2 among severe intraabdominal sepsis. Patients and methods: This prospective study included 62 patients with intraabdominal sepsis who were presented at the Emergency Hospital Mansoura University for one year duration. PvaCO2 and ScvO2 values were assessed at admission and every 6 hours till the end of 48 hours. Results: The PvaCO2 showed significant high levels among the survivor group compared to with the mortality group at 6-48 Hours. Among the included patients, the non survivors tended to have either above or below normal levels of ScvO2 at 6-48 hours. Multivariate analysis showed that decreased PvaCO2, increased APACHE-II score, increased SOFA score and increased qSOFA score at admission were shown as independent risk predictors for mortality. Conclusion: Elevated PvaCO2, above and below normal ScvO2 levels are associated with poor outcomes and raised risk of mortality. Thus, they hold promise as prognostic values in severe sepsis patients. | ||||
| Keywords | ||||
| Intraabdominal Sepsis; PvaCO2; ScvO2 | ||||
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