Evaluation of cross-protection between FMD serotypes O and A local Egyptian isolate with vaccinal strains in the local commercial and imported vaccines by challenge test | ||
| Benha Veterinary Medical Journal | ||
| Article 28, Volume 28, Issue 1, March 2015, Pages 241-246 PDF (212.52 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/bvmj.2015.32757 | ||
| Authors | ||
| Gabr F. El-Bagoury1; Saad S.A Sharawi1; Ehab M. El-Nahas1; Darwish M. Darwish2; Mohammed A. Saad2 | ||
| 1Department of virology, Faculty of Veterinary Medicine, Benha University | ||
| 2Veterinary Serum and Vaccine Research Institute, Abbassia, Cairo | ||
| Abstract | ||
| Foot-and-mouth disease (FMD) is a highly contagious and economically devastating viral disease of cloven-hoofed animals. In Egypt, the local commercial (trivalent O Panasia-2/A Iran-05/ SAT2/EGYA- 2012) and imported (trivalent O Manisa /A Iran-05/ SAT2/EGY-A-2012) inactivated vaccines were used for rapid control of the disease. We aimed to determine the cross protection between FMD virus serotypes O and A local Egyptian isolate with vaccinal strains in the local commercial and imported vaccines using challenge experiment. By the 7th day post challenge with either O/EGY-4-2012 or A/EGY/1/2012 isolates, the vaccinated cattle with either local commercial or imported vaccine were clinically protected by 100% with local commercial vaccine and 80% with imported vaccine for O/EGY- 4-2012. The protection values were 100% and 80% with cattle challenged with A/EGY/1/2012 and vaccinated with a local commercial or imported vaccine respectively. In conclusion, FMD virus Egyptian isolates O and A was antigenically similar to that of vaccinal strains in local commercial and imported vaccines which provide good protection | ||
| Keywords | ||
| Foot-and-mouth disease; cross protection; serotypes O and A; vaccinal strains | ||
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