Evaluation of cross-protection between FMD serotypes O and A local Egyptian isolate with vaccinal strains in the local commercial and imported vaccines by challenge test
El-Bagoury, G., Sharawi, S., El-Nahas, E., Darwish, D., Saad, M. (2015). Evaluation of cross-protection between FMD serotypes O and A local Egyptian isolate with vaccinal strains in the local commercial and imported vaccines by challenge test. EKB Journal Management System, 28(1), 241-246. doi: 10.21608/bvmj.2015.32757
Gabr F. El-Bagoury; Saad S.A Sharawi; Ehab M. El-Nahas; Darwish M. Darwish; Mohammed A. Saad. "Evaluation of cross-protection between FMD serotypes O and A local Egyptian isolate with vaccinal strains in the local commercial and imported vaccines by challenge test". EKB Journal Management System, 28, 1, 2015, 241-246. doi: 10.21608/bvmj.2015.32757
El-Bagoury, G., Sharawi, S., El-Nahas, E., Darwish, D., Saad, M. (2015). 'Evaluation of cross-protection between FMD serotypes O and A local Egyptian isolate with vaccinal strains in the local commercial and imported vaccines by challenge test', EKB Journal Management System, 28(1), pp. 241-246. doi: 10.21608/bvmj.2015.32757
El-Bagoury, G., Sharawi, S., El-Nahas, E., Darwish, D., Saad, M. Evaluation of cross-protection between FMD serotypes O and A local Egyptian isolate with vaccinal strains in the local commercial and imported vaccines by challenge test. EKB Journal Management System, 2015; 28(1): 241-246. doi: 10.21608/bvmj.2015.32757

Evaluation of cross-protection between FMD serotypes O and A local Egyptian isolate with vaccinal strains in the local commercial and imported vaccines by challenge test

Benha Veterinary Medical Journal
Article 28, Volume 28, Issue 1, March 2015, Page 241-246  XML PDF (212.52 K)
Document Type: Original Article
DOI: 10.21608/bvmj.2015.32757
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Authors
Gabr F. El-Bagoury1; Saad S.A Sharawi1; Ehab M. El-Nahas1; Darwish M. Darwish2; Mohammed A. Saad2
1Department of virology, Faculty of Veterinary Medicine, Benha University
2Veterinary Serum and Vaccine Research Institute, Abbassia, Cairo
Abstract
Foot-and-mouth disease (FMD) is a highly contagious and economically devastating viral disease of
cloven-hoofed animals. In Egypt, the local commercial (trivalent O Panasia-2/A Iran-05/ SAT2/EGYA-
2012) and imported (trivalent O Manisa /A Iran-05/ SAT2/EGY-A-2012) inactivated vaccines were
used for rapid control of the disease. We aimed to determine the cross protection between FMD virus
serotypes O and A local Egyptian isolate with vaccinal strains in the local commercial and imported
vaccines using challenge experiment. By the 7th day post challenge with either O/EGY-4-2012 or
A/EGY/1/2012 isolates, the vaccinated cattle with either local commercial or imported vaccine were
clinically protected by 100% with local commercial vaccine and 80% with imported vaccine for O/EGY-
4-2012. The protection values were 100% and 80% with cattle challenged with A/EGY/1/2012 and
vaccinated with a local commercial or imported vaccine respectively. In conclusion, FMD virus
Egyptian isolates O and A was antigenically similar to that of vaccinal strains in local commercial and
imported vaccines which provide good protection
Keywords
Foot-and-mouth disease; cross protection; serotypes O and A; vaccinal strains
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