Advancements in Skin Aging Treatment: Exploring Antioxidants and Nanoparticles for Enhanced Skin Permeation | ||
| Archives of Pharmaceutical Sciences Ain Shams University | ||
| Volume 7, Issue 2, December 2023, Pages 376-401 PDF (667.45 K) | ||
| Document Type: Review Article | ||
| DOI: 10.21608/aps.2023.250333.1146 | ||
| Authors | ||
| Raghda M. Elsisi1, 2; Dina O. Helal* 1; George M. Mekhail1, 3; Dalia M. N. Abouhussein2; Amany O. Kamel1 | ||
| 1Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Ain Shams University, Cairo 11566, Egypt. | ||
| 2Egyptian drug authority (EDA), Cairo, Egypt. | ||
| 3University of Waterloo, 200 University Avenue West, School of Pharmacy, Waterloo, ON, N2L 3G1, Canada. | ||
| Abstract | ||
| Many people have always aspired to have skin that is young-looking and vibrant. The natural aging process of the skin, which is impacted by both internal and external factors, has sparked further research into its origins and the creation of efficient therapeutic approaches. This review aims to give a thorough understanding of the skin's composition, the causes and variables that contribute to skin aging, the difficulties in treating skin aging, and the methods used to treat skin aging. It will also go into detail about the obstacles antioxidants face while trying to permeate the skin and their potential role as essential players in the fight against skin aging. In addition, it will discuss the intriguing use of nanoparticles (NPs) in reversing skin aging, emphasizing their involvement in enhanced skin penetration. Due to their distinct size-dependent characteristics and ability to integrate medicines, NPs in general provide a variety of therapeutic benefits for antioxidant drug delivery to control skin aging. | ||
| Keywords | ||
| Drug delivery; Wrinkles; Oxidative stress; Nanoscale particles; Topical delivery | ||
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