Comparison of analgesic efficacy of perineural dexamethasone in rectus sheath block and intravenous dexamethasone with levobupivacaine in bilateral rectus sheath block for patients undergoing midline abdominal surgery: a randomized controlled trial
Singariya, G., Saini, P., Choudhary, U., Kamal, M., Bihani, P., Choudhary, K., Khatri, C. (2023). Comparison of analgesic efficacy of perineural dexamethasone in rectus sheath block and intravenous dexamethasone with levobupivacaine in bilateral rectus sheath block for patients undergoing midline abdominal surgery: a randomized controlled trial. EKB Journal Management System, 15(1), -. doi: 10.1186/s42077-023-00353-3
Geeta Singariya; Pradeep Kumar Saini; Usha Choudhary; Manoj Kamal; Pooja Bihani; Kusum Choudhary; Chanda Khatri. "Comparison of analgesic efficacy of perineural dexamethasone in rectus sheath block and intravenous dexamethasone with levobupivacaine in bilateral rectus sheath block for patients undergoing midline abdominal surgery: a randomized controlled trial". EKB Journal Management System, 15, 1, 2023, -. doi: 10.1186/s42077-023-00353-3
Singariya, G., Saini, P., Choudhary, U., Kamal, M., Bihani, P., Choudhary, K., Khatri, C. (2023). 'Comparison of analgesic efficacy of perineural dexamethasone in rectus sheath block and intravenous dexamethasone with levobupivacaine in bilateral rectus sheath block for patients undergoing midline abdominal surgery: a randomized controlled trial', EKB Journal Management System, 15(1), pp. -. doi: 10.1186/s42077-023-00353-3
Singariya, G., Saini, P., Choudhary, U., Kamal, M., Bihani, P., Choudhary, K., Khatri, C. Comparison of analgesic efficacy of perineural dexamethasone in rectus sheath block and intravenous dexamethasone with levobupivacaine in bilateral rectus sheath block for patients undergoing midline abdominal surgery: a randomized controlled trial. EKB Journal Management System, 2023; 15(1): -. doi: 10.1186/s42077-023-00353-3

Comparison of analgesic efficacy of perineural dexamethasone in rectus sheath block and intravenous dexamethasone with levobupivacaine in bilateral rectus sheath block for patients undergoing midline abdominal surgery: a randomized controlled trial

Ain-Shams Journal of Anesthesiology
Volume 15, Issue 1, January 2023  XML PDF (1.25 MB)
DOI: 10.1186/s42077-023-00353-3
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Authors
Geeta Singariya email orcid ; Pradeep Kumar Sainiorcid ; Usha Choudharyorcid ; Manoj Kamalorcid ; Pooja Bihaniorcid ; Kusum Choudharyorcid ; Chanda Khatriorcid
Abstract
Background
Dexamethasone is used in regional analgesia to prolong the duration of analgesia and anaesthesia. The perineural and intravenous (IV) dexamethasone in fascial plane block have conflicting results. The study aimed to compare analgesic efficacy of perineurally and intravenously dexamethasone in rectus sheath block (RSB). This prospective, double-blinded, randomized control study was conducted in 105 patients, equally divided in three groups. All the patients received ultrasound-guided RSB block with 20 ml of 0.25% levobupivacaine on each side. Additionally, in group A, 1-ml normal saline (NS) on each side in RSB block and 2-ml NS IV; in group B, 4-mg dexamethasone on each side in RSB block and 2-ml NS IV; and in group C, 1-ml NS on each side in RSB block and 8-mg dexamethasone IV.
Results
The duration of analgesia was maximum in group B (935.91 ± 121.82 min) and then in group C (730.31 ± 129.64 min) and group A (418.34 ± 29.22 min) ( < 0.0001). The morphine consumption and mean NRS score (at rest and cough) were lowest in group B and then group C and group A ( < 0.0001).
Conclusions
The perineural dexamethasone as an adjuvant to levobupivacaine prolongs the duration of analgesia with decreased analgesic requirements compared to intravenous dexamethasone in bilateral RSB in patients undergoing midline laparotomy surgery.
Keywords
dexamethasone; Levobupivacaine; Laparotomies; Analgesia; Rectus Sheath Block
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