Curcumin Mimics: An Overview | ||
| Records of Pharmaceutical and Biomedical Sciences | ||
| Volume 7, Issue 1, January 2023, Pages 189-196 PDF (539.28 K) | ||
| Document Type: Mini-reviews | ||
| DOI: 10.21608/rpbs.2023.246345.1251 | ||
| Authors | ||
| Ranza Ahmed Elrayess* 1; Sherief M. Abdel-Wahab2; Asmaa SA Yassen3; Khadiga M Attia2; Hosam A. Elshihawy3 | ||
| 1Department of Pharmaceutical organic chemistry, faculty of pharmacy, Suez canal University, Ismailia, Egypt | ||
| 2Pharmaceutical Organic Chemistry Department, College of Pharmaceutical Sciences and Drug Manufacturing, Misr University for Science and Technology, Giza, Egypt | ||
| 3Pharmaceutical Organic Chemistry, School of Pharmacy, Suez Canal University | ||
| Abstract | ||
| Curcumin is a natural product which is isolated from curcuma longa, it was used for several centuries as an anti-inflammatory agent in traditional medicine. Curcumin has several activities including anti-inflammatory, antioxidant, antibacterial and anticancer activity. However, bioavailability, stability and selectivity problems associated with curcumin limited their use, that is why a great effort was done to develop curcumin mimics that overcome these problems. In this review, we will illustrate some different biological activities of curcumin mimetics. Curcumin is a natural product which is isolated from curcuma longa, it was used for several centuries as an anti-inflammatory agent in traditional medicine. Curcumin has several activities including anti-inflammatory, antioxidant, antibacterial and anticancer activity. However, bioavailability, stability and selectivity problems associated with curcumin limited their use, that is why a great effort was done to develop curcumin mimics that overcome these problems. In this review, we will illustrate some different biological activities of curcumin mimetics. | ||
| Keywords | ||
| Curcumin; Anti-cancer; Anti-inflammatory; Curcumin mimetics | ||
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