HOMA-IR INDEX IN INDUSTRIAL SHIFT WORKERS, A PRELIMINARY STUDY | ||
| Journal of Environmental Science | ||
| Volume 52, Issue 12, December 2023, Pages 1-14 PDF (517.03 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/jes.2023.237546.1630 | ||
| Authors | ||
| Maria S. Ayoub* 1; Hala I. Awadalla* 2; Wael M. Elsayed* 3; Eman A. Sultan* 4 | ||
| 1Faculty of Graduate Studies and Environmental Research, Ain Shams University, Ahram Canadian University | ||
| 2Faculty of Graduate Studies and Environmental Research, Ain Shams University, Egypt | ||
| 3Faculty of Medicine, Ain Shams University, Egypt | ||
| 4National Nutrition Institute, Egypt | ||
| Abstract | ||
| There is strong evidence suggesting a probable association between shift work (SW) and insulin resistance (IR). Hence, it is crucial to evaluate this factor in therapeutic and preventive interventions. In a comparative cross-sectional study, serum fasting glucose levels and serum fasting insulin hormone levels were estimated, then Homeostatic Model Assessment for Insulin Resistance (HOMA-IR) index was examined among shift workers (SWs) employed in the industrial sector. An occupational surveillance framework included 60 industrial workers, who were classified as follows: thirty were shift workers (SWs) and thirty were non-shift workers (NSWs). Fasting blood sugar and fasting serum insulin hormone levels were estimated, and HOMA-IR Index was calculated for all participants and the results were investigated for a possible link with shift work. A significantly higher serum fasting insulin level as well as a high HOMA-IR index was observed among SWs as a result (p<0.05). Accordingly, Shift work may raise the potential for developing insulin resistance. Keywords: Diabetes Mellitus; Insulin resistance; Workers; Night work; Shift work; Circadian clock. | ||
| Keywords | ||
| Diabetes Mellitus; Insulin resistance; Workers; Night work; Shift work; Circadian clock | ||
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