Evaluating the Analgesic Efficacy of Magnesium Sulfate in Quadratus Lumborum Block for Mild Pre-eclampsia during Cesarean Section | ||||
| Minia Journal of Medical Research | ||||
| Articles in Press, Accepted Manuscript, Available Online from 27 December 2023 | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/mjmr.2023.254126.1558 | ||||
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| Authors | ||||
Ashraf Hamdy Ismail  1; Ibrahim Talaat2; George Abdel-Shaheed Yakoub3
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| 1Anesthesia and ICU department, Faculty of Medicine, Minia University, Minia | ||||
| 2Anesthesia and ICU department, Minia University | ||||
| 3Anesthesia and intensive care department ,Minia University, Minia university hospital,Minia, Egypt | ||||
| Abstract | ||||
| The escalating global rates of cesarean sections underscore the imperative to address postoperative pain management, particularly in the context of pre-eclampsia, a pregnancy-specific complication with inherent risks. This study, conducted at Minya University Hospital from October 2021 to April 2023, investigated the analgesic efficacy of combining magnesium sulfate with bupivacaine in quadratus lumborum block for mild pre-eclampsia during cesarean section. Eighty ASA grade II women participated in this double-blind, controlled study, with random group assignments. The assessment criteria included the Visual Analog Scale (VAS) for pain, hemodynamic monitoring, and observation of adverse effects. The results demonstrated comparable demographics and hemodynamic parameters between groups, emphasizing the safety of the intervention. Importantly, VAS scores at 8, 12, 18, 24, and 48 hours post-surgery favored the magnesium sulfate group (p<0.05), indicating superior analgesic efficacy without observed complications. This study contributes novel insights, suggesting that the combination of magnesium sulfate with bupivacaine in quadratus lumborum block offers a promising opioid-sparing strategy for postoperative pain management in mild pre-eclampsia during cesarean section. The observed benefits are particularly noteworthy, as they align with the global need for alternatives to traditional opioid-based analgesia, especially in populations with unique considerations such as pregnant women. Further research is warranted to validate and expand upon these findings, potentially influencing clinical approaches for enhancing maternal well-being in this specific patient population. | ||||
| Keywords | ||||
| Cesarean section; pre-eclampsia; neuraxial anesthesia; quadratus lumborum block; magnesium sulfate | ||||
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