ISOLATION OF COMMON CONTAMINANTS FROM VETERINARY BIOLOGICAL PRODUCTS AND THEIR SIGNIFICANCE | ||
| Egyptian Journal of Agricultural Research | ||
| Article 33, Volume 77, Issue 3, September 1999, Pages 1385-1397 PDF (2.75 M) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ejar.1999.337761 | ||
| Authors | ||
| SAMY M. SHAFAY; ELHAM A. EL-EBIARY | ||
| Central Laboratory for control of Veterinary Biologics, Agricultural Research Centre, Egypt | ||
| Abstract | ||
| Eight-hundred and thirty three (833) samples of biological products ("31 5" live attenuated egg adapted vaccines, "1 93" live attenuated tissue culture adapted vaccines, "268" inactivated vaccines, "12" antigens, "9" anti-tetanic serum, 11 normal serum (neoborn calf serum, fetal calf serum, horse and swine serum and "25" physiological saline) were screened against common contaminants (Bacterial, Fungal and Mycoplasmal), and antibiotic sensitivity to these contaminants were determined. The results revealed that, out of the total number of samples (833), 18 samples (2.2%) were contaminated with various types of contaminants (anthracoid "6", proteus "5", fungus "2", staphylococci 2, E.coli1, Mycoplasma 1 and streptococci 1). Concerning the results of antibiotic sensitivity test, it was clear that anthracoid, proteus, fungi, E.coli and Mycoplasma were sensitive to chloramphenicol, P-nitrophenyl glycerol, mycostatine, amoxycillin, and lincospectin, respectively, with varying degrees. Staphylococci and streptococci contaminants were sensitive to benzyl penicillin. By application of this study, it is possible to control the contaminants which interfere the production of different veterinary biologics. | ||
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