Relation Between Kidney Injury Molecule 1 (KIM 1) And Diabetic Nephropathy
Ahmed, M., Abdullah, N., Mostafa, S., Abd Elaal, A., Matar, H. (2024). Relation Between Kidney Injury Molecule 1 (KIM 1) And Diabetic Nephropathy. EKB Journal Management System, 5(1), 80-91. doi: 10.21608/ejmr.2024.254949.1507
Mahmoud Hassan Ahmed; Nilly Helmy Abdullah; Sara Osama Mostafa; Ahmed Taha Abd Elaal; Hazem Samy Matar. "Relation Between Kidney Injury Molecule 1 (KIM 1) And Diabetic Nephropathy". EKB Journal Management System, 5, 1, 2024, 80-91. doi: 10.21608/ejmr.2024.254949.1507
Ahmed, M., Abdullah, N., Mostafa, S., Abd Elaal, A., Matar, H. (2024). 'Relation Between Kidney Injury Molecule 1 (KIM 1) And Diabetic Nephropathy', EKB Journal Management System, 5(1), pp. 80-91. doi: 10.21608/ejmr.2024.254949.1507
Ahmed, M., Abdullah, N., Mostafa, S., Abd Elaal, A., Matar, H. Relation Between Kidney Injury Molecule 1 (KIM 1) And Diabetic Nephropathy. EKB Journal Management System, 2024; 5(1): 80-91. doi: 10.21608/ejmr.2024.254949.1507

Relation Between Kidney Injury Molecule 1 (KIM 1) And Diabetic Nephropathy

Egyptian Journal of Medical Research
Volume 5, Issue 1, January 2024, Pages 80-91    PDF (831.49 K)
Document Type: Original Article
DOI: 10.21608/ejmr.2024.254949.1507
Authors
Mahmoud Hassan Ahmed1; Nilly Helmy Abdullah1; Sara Osama Mostafa2; Ahmed Taha Abd Elaal* 1; Hazem Samy Matar1
1Department of Internal Medicine, Faculty of Medicine, Beni-Suef University.
2Department of Clinical and Chemical Pathology, Faculty of Medicine, Beni-Suef University.
Abstract
Background: Diabetic nephropathy is a chronic disorder that takes years to develop and is characterized by a progressive rise in urinary albumin secretion. It is one of the primary consequences of diabetes mellitus. Aim and objectives: To investigate the relation between kidney injury molecule1 (KIM1) and diabetic nephropathy. Patients and methods: This was a case control research performed on 100 subjects at internal medicine department of beni-suef university hospital. Thecases were separated into 4 groups. Results: KIM -1 showed  statistically significant varianceamongst the four studied groups with P value ( <0.001) ;In Control group KIM-1 varied from 1.70 to 27.50 with mean ± SD = 12.21 ± 7.249 , In normo-albuminuric group  KIM-1 ranged from 21 to 36.90 with mean  ± SD = 27.11 ± 4.48 ,  in micro-albuminuric group KIM-1 ranged from 10.1 to 53 with mean ± SD= 42.8 ± 9.33,inmacro- albuminuric group KIM-1 ranged from.69.to 81.5 with mean ± SD = 75.5 ± 4.03. Conclusion:Our study revealed increase of serum KIM 1 levels with development of Diabetic Nephropathy, reflecting the important role of Kim-1-as a biomarker for early diagnosis-and progression of DN. Serum Kim-1 is recommended to be utilized as a warning system for the development of diabetic nephropathy in people with diabetes as a screening test.
Keywords
KIM 1; Diabetic Nephropathy; Relation
References

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