Probiotics: Mitigating antibiotic resistance in the vaginal microbiome
Ezeanya-Bakpa, C., Udeogu, C., Agbakoba, N., Uduchi, I., Ejike, C. (2024). Probiotics: Mitigating antibiotic resistance in the vaginal microbiome. EKB Journal Management System, 5(3), 1036-1045. doi: 10.21608/mid.2024.266564.1782
Chinyere Charity Ezeanya-Bakpa; Chidozie Udeogu; Nneka Regina Agbakoba; Immaculata Uduchi; Chinwe Ejike. "Probiotics: Mitigating antibiotic resistance in the vaginal microbiome". EKB Journal Management System, 5, 3, 2024, 1036-1045. doi: 10.21608/mid.2024.266564.1782
Ezeanya-Bakpa, C., Udeogu, C., Agbakoba, N., Uduchi, I., Ejike, C. (2024). 'Probiotics: Mitigating antibiotic resistance in the vaginal microbiome', EKB Journal Management System, 5(3), pp. 1036-1045. doi: 10.21608/mid.2024.266564.1782
Ezeanya-Bakpa, C., Udeogu, C., Agbakoba, N., Uduchi, I., Ejike, C. Probiotics: Mitigating antibiotic resistance in the vaginal microbiome. EKB Journal Management System, 2024; 5(3): 1036-1045. doi: 10.21608/mid.2024.266564.1782

Probiotics: Mitigating antibiotic resistance in the vaginal microbiome

Microbes and Infectious Diseases
Article 16, Volume 5, Issue 3, August 2024, Page 1036-1045  XML PDF (545.22 K)
Document Type: Review Article
DOI: 10.21608/mid.2024.266564.1782
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Authors
Chinyere Charity Ezeanya-Bakpa email orcid 1; Chidozie Udeoguorcid 2; Nneka Regina Agbakobaorcid 2; Immaculata Uduchiorcid 2; Chinwe Ejikeorcid 3
1Department of Microbiology and Biotechnology, Caleb University Lagos, Nigeria.
2Department of Medical Laboratory Science, Nnamdi Azikiwe University, Awka, Nigeria
3Department of Medical Microbiology, Chukwuemeka Odumegwu Ojukwu University, Nigeria
Abstract
Background:  Studies have shown a strong correlation between probiotics and incidence of antibiotic resistance. Many studies have reported antibiotic resistance in the vaginal microbiome especially in women with dysbiosis condition, and it is possible that the antibiotic resistance plays a role in the alteration of the vaginal microbiome and disease complications. Consequently, this study aims to investigate the vaginal microbiome with antibiotic resistance in healthy, menopausal and post-menopausal women and the mitigating effect of probiotics. In this narrative review, a comprehensive review of web of science, PubMed, Scientific information database, Google scholar and Scopus with no time limit. The keyword “Probiotics”, “Antibiotic resistance”, “Vaginal Microbiome”, “Vaginal Microbiota” were used to provide a synopsis of mitigating antibiotic resistance in the vaginal microbiome. Among the 917 sources identified, 12 articles were found most appropriate for the study. Our findings recommend administration of probiotics to alleviate antibiotic resistance. The study revealed that probiotics may mitigate antibiotic resistance in the vaginal microbiome and possibly improve the female reproductive health at all levels including menopausal and post- menopausal.
Keywords
Probiotics; Vaginal Microbiome; Vaginal Microbiota; Antibiotic resistance; Mitigation
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