The effect of different instrumentation kinematics on the change in substance P levels in patients with symptomatic apical periodontitis. A randomized controlled trial | ||
| Egyptian Dental Journal | ||
| Volume 70, Issue 2 - Serial Number 5, April 2024, Pages 1837-1845 PDF (1.42 M) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/edj.2024.252735.2812 | ||
| Authors | ||
| salma abdelbaset* 1; maram Obeid2; Sarah Hossam Fahmy3 | ||
| 1MSc student, Department of Endodontics, Faculty of Dentistry, Ain Shams University, Cairo, Egyp | ||
| 2Professor, Department of Endodontics, Faculty of Dentistry, Ain Shams University, Cairo, Egypt. | ||
| 3Lecturer, Department of Endodontics, Faculty of Dentistry, Ain Shams University, Cairo, Egypt. | ||
| Abstract | ||
| Aim: This study aimed to assess the influence of continuous rotation and reciprocation kinematics on the change in substance P (SP) levels in patients diagnosed with irreversible pulpitis and symptomatic apical periodontitis (SAP). Materials and methods: A total of twenty patients were randomly assigned into two groups: Continuous Rotation Group (CG) (n=10), where mechanical preparation was performed with the EdgeEndox7 rotary system (Albuquerque, NM, USA), and Reciprocation Group (RG) (n=10), with EdgeOne Fire reciprocating system (Albuquerque, NM, USA). Apical fluid (AF) samples were collected and changes in SP levels were quantified through ELISA. Data were statistically analyzed utilizing the independent t-test, Friedman’s test, and Nemenyi post hoc test. Results: The difference of SP levels in the reciprocating group was significantly higher when compared to the continuous rotation group (P≤ 0.05) when measured preoperatively and at the beginning of the second visit. Conclusion: Our findings suggest that continuous rotation kinematics lead to a reduction in substance P levels. | ||
| Keywords | ||
| continuous rotation; reciprocation; substance P; apical periodontitis | ||
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