THE EFFECT OF BONE MARROW ASPIRATE CONCENTRATE IN THE TREATMENT OF MANDIBULAR CYSTIC DEFECTS. A RANDOMIZED CLINICAL TRIAL | ||
| Alexandria Dental Journal | ||
| Article 10, Volume 49, Issue 2, August 2024, Pages 73-81 PDF (393.76 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/adjalexu.2023.195418.1353 | ||
| Authors | ||
| Ahmed Ahmed ElSafty* 1; Samraa A. Elsheikh2; Ahmed O Sweedan2 | ||
| 1Oral and Maxillofacial surgery, Faculty of Dentistry, Alexandria University Alexandria, Egypt | ||
| 2Oral and Maxillofacial Surgery Department, Faculty of Dentistry, Alexandria University, Egypt. | ||
| Abstract | ||
| Objective: To evaluate the effect of bone marrow aspirate concentrate in the treatment of mandibular cystic defects in comparison to the spontaneous healing using clinical and radiographic parameters. Materials and methods: 16 patients having mandibular radiolucency’s diagnosed by aspiration biopsy were divided equally into two groups. Group A included patients whom treated by enucleation and filling the defect by bone marrow aspirate concentrate on a collagen sponge, and group B included those treated conventionally. Clinical follow up was conducted, with a radiographic examination that was performed immediately post-operative and after 3 and 6 months to estimate the mean bone density and the reduction in the defect volume. Results: The study was conducted on 16 patients with male-to-female ratio of 1:1.66 and average age of 28.94. The intergroup comparison of bone density was insignificant across the follow-up period. The defect’s volume analysis showed a significant difference in the reduction between the two groups across the follow-up period. The volume reduction difference between the two groups was statistically significant (P= 0.002). Conclusion: The use of bone marrow aspirate concentrate in mandibular defects is a safe and minimally invasive procedure to enhance bone healing for better healing of the defect and improvement in bone density. The operation showed adequate clinical and radiographic performance. | ||
| Keywords | ||
| bone marrow aspirate concentrate; mandibular defects; mandibular cysts | ||
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