The Role of Anti-Nuclear Antibodies in Recurrent Abortion of Immunological Origin
El-Baz Ahmed, A., Ibrahim, M., Ali Zidan, A., Mohamed Basha, A. (2025). The Role of Anti-Nuclear Antibodies in Recurrent Abortion of Immunological Origin. EKB Journal Management System, 31(1.1), 333-338. doi: 10.21608/zumj.2024.274116.3223
Amira El-Sayed Masoud El-Baz Ahmed; Mohamed Abdel-Moniem Ibrahim; Amal Ahmed Ali Zidan; Ahlam Ahmed Mohamed Basha. "The Role of Anti-Nuclear Antibodies in Recurrent Abortion of Immunological Origin". EKB Journal Management System, 31, 1.1, 2025, 333-338. doi: 10.21608/zumj.2024.274116.3223
El-Baz Ahmed, A., Ibrahim, M., Ali Zidan, A., Mohamed Basha, A. (2025). 'The Role of Anti-Nuclear Antibodies in Recurrent Abortion of Immunological Origin', EKB Journal Management System, 31(1.1), pp. 333-338. doi: 10.21608/zumj.2024.274116.3223
El-Baz Ahmed, A., Ibrahim, M., Ali Zidan, A., Mohamed Basha, A. The Role of Anti-Nuclear Antibodies in Recurrent Abortion of Immunological Origin. EKB Journal Management System, 2025; 31(1.1): 333-338. doi: 10.21608/zumj.2024.274116.3223

The Role of Anti-Nuclear Antibodies in Recurrent Abortion of Immunological Origin

Zagazig University Medical Journal
Article 37, Volume 31, Issue 1.1, January 2025, Page 333-338  XML PDF (1.07 MB)
Document Type: Original Article
DOI: 10.21608/zumj.2024.274116.3223
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Authors
Amira El-Sayed Masoud El-Baz Ahmed email 1; Mohamed Abdel-Moniem Ibrahim2; Amal Ahmed Ali Zidan3; Ahlam Ahmed Mohamed Basha2
1Department of Obstetrics & Gynecology, Faculty of Medicine Zagazig University, Egypt.
2Department of Obstetrics & Gynecology, Faculty of Medicine, Zagazig University, Egypt.
3Department of Clinical Pathology, Faculty of Medicine, Zagazig University, Egypt.
Abstract
Background: Recurrent pregnancy loss (RPL) is the happening of two or more miscarriage events before the 20th week of pregnancy. This research aimed to assess the role of ANA in recurrent pregnancy loss of immunologic origin in Egyptian pregnant females.

Patients and methods: This was a case-control research performed on 70 women in their first trimester of pregnancy at Zagazig University Hospitals. Patients were subdivided into 2 groups.

Results: There was a significant association between RPL and both positivity of ANA (OR=4.337, p=.076) and parity (OR= 1.62, p=.054) at significance level of 0.1 which is acceptable as non-standard p-value, that means a female with positive ANA test has 4.3 times chances to have RPL compared to a female with negative ANA test, also females with each one increase in number of previous successful given births (parity) has a correspondent 1.621 times increase of probability to have recurrent pregnancy loss

Conclusion: (ANA) has important role in prognosis recurrent pregnancy loss. Therefore, we can benefit from Examination ANA to diagnose or predict a threatened miscarriage.
Keywords
Anti-Nuclear Antibodies; Recurrent Abortion; immunological abortion
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