Assessment of Leptin Level in Serum of Patients with Seborrheic Dermatitis | ||||
| Benha Journal of Applied Sciences | ||||
| Article 19, Volume 9, Issue 2, February 2024, Page 145-147 PDF (760.81 K) | ||||
| Document Type: Original Research Papers | ||||
| DOI: 10.21608/bjas.2024.279329.1372 | ||||
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| Authors | ||||
Menna A.Soliman  1; Asmaa M.Al Refaei2; Ghada M. Abdel Khalik1; Maha T. Rachwan2
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| 1Dermatology, Venereolgoy and Andrology Department, Faculty of Medicine, Benha University | ||||
| 2Clinical and Chemical Pathology Department, Faculty of Medicine, Benha University | ||||
| Abstract | ||||
| Background: Seborrheic dermatitis (SD) is a prevalent dermatological condition encountered in medical settings, known by various names such as sebo psoriasis, seborrheic eczema, and dandruff, among others. the rising prevalence of metabolic syndrome (MetS) poses a global health challenge, with emerging interest in its connection to various dermatological conditions, including SD, conditions like obesity are associated with increased leptin levels and resistance to its action, suggesting a complex interaction between leptin and skin health. Objective: This review aims to assess serum level of leptin in patients with SD and its relation to MetS in these patients, if any. Conclusions: patients with seborrheic dermatitis exhibit significantly higher serum leptin levels compared to healthy controls, indicating a potential role of leptin in the pathogenesis of the disease. Notably, serum leptin levels correlated with the severity of the disease and showed potential as a biomarker for disease severity. | ||||
| Keywords | ||||
| Seborrheic dermatitis; Leptin; Metabolic syndrome | ||||
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