Assessment of Leptin Level in Serum of Patients with Seborrheic Dermatitis | ||
| Benha Journal of Applied Sciences | ||
| Article 19, Volume 9, Issue 2, February 2024, Pages 145-147 PDF (760.81 K) | ||
| Document Type: Original Research Papers | ||
| DOI: 10.21608/bjas.2024.279329.1372 | ||
| Authors | ||
| Menna A.Soliman* 1; Asmaa M.Al Refaei2; Ghada M. Abdel Khalik1; Maha T. Rachwan2 | ||
| 1Dermatology, Venereolgoy and Andrology Department, Faculty of Medicine, Benha University | ||
| 2Clinical and Chemical Pathology Department, Faculty of Medicine, Benha University | ||
| Abstract | ||
| Background: Seborrheic dermatitis (SD) is a prevalent dermatological condition encountered in medical settings, known by various names such as sebo psoriasis, seborrheic eczema, and dandruff, among others. the rising prevalence of metabolic syndrome (MetS) poses a global health challenge, with emerging interest in its connection to various dermatological conditions, including SD, conditions like obesity are associated with increased leptin levels and resistance to its action, suggesting a complex interaction between leptin and skin health. Objective: This review aims to assess serum level of leptin in patients with SD and its relation to MetS in these patients, if any. Conclusions: patients with seborrheic dermatitis exhibit significantly higher serum leptin levels compared to healthy controls, indicating a potential role of leptin in the pathogenesis of the disease. Notably, serum leptin levels correlated with the severity of the disease and showed potential as a biomarker for disease severity. | ||
| Keywords | ||
| Seborrheic dermatitis; Leptin; Metabolic syndrome | ||
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