Analytical Methods of Some Calcium Channel Blockers. A Brief Review.
roshdy, A., abdel salam, R., Hadad, G., Belal, F., Elmansi, H. (2024). Analytical Methods of Some Calcium Channel Blockers. A Brief Review.. EKB Journal Management System, 8(1), 1-15. doi: 10.21608/rpbs.2024.240973.1245
aya R roshdy; randa abdel salam; Ghada Hadad; Fathalla Belal; heba Elmansi. "Analytical Methods of Some Calcium Channel Blockers. A Brief Review.". EKB Journal Management System, 8, 1, 2024, 1-15. doi: 10.21608/rpbs.2024.240973.1245
roshdy, A., abdel salam, R., Hadad, G., Belal, F., Elmansi, H. (2024). 'Analytical Methods of Some Calcium Channel Blockers. A Brief Review.', EKB Journal Management System, 8(1), pp. 1-15. doi: 10.21608/rpbs.2024.240973.1245
roshdy, A., abdel salam, R., Hadad, G., Belal, F., Elmansi, H. Analytical Methods of Some Calcium Channel Blockers. A Brief Review.. EKB Journal Management System, 2024; 8(1): 1-15. doi: 10.21608/rpbs.2024.240973.1245

Analytical Methods of Some Calcium Channel Blockers. A Brief Review.

Records of Pharmaceutical and Biomedical Sciences
Volume 8, Issue 1, 2024, Page 1-15  XML PDF (679.34 K)
Document Type: Mini-reviews
DOI: 10.21608/rpbs.2024.240973.1245
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Authors
aya R roshdy email orcid 1; randa abdel salamorcid 2; Ghada Hadadorcid 2; Fathalla Belal3; heba Elmansi4
1Horus university
2Analytical Chemistry Department, Faculty of Pharmacy, Suez Canal University, Ismailia, 41522, Egypt.
3Faculty of Pharmacy -Mansora University
4Mansoura
Abstract
Calcium channel blockers (CCBs) are a class of pharmaceutical compounds frequently used to treat a variety of cardiovascular and neurological problems. For such drugs to be therapeutically effective and patient-safe, their exact and accurate determination is essential. A detailed description of the analytical methods used to determine three of the calcium channel blockers, namely, lercanidipine, Nimodipine and Nifedipineis provided in a brief review article with 101 references.It includes a thorough review of research articles published up to September 2023. High-performance liquid chromatography, gas chromatography, electrochemical, capillary electrophoresis and spectroscopic techniques including UV-Visible and spectrofluorometry are only a few of the analytical methods covered in the paper. These techniques provide excellent CCB quantification in a variety of matrices with high sensitivity, specificity, and reproducibility. In order to perform precise and reliable analysis of these CCBs, the research emphasizes the significance of sample preparation procedures, extraction methodologies, and validation criteria. Additionally, it explores current developments in analytical instrumentation and how they can be used to analyze lercanidipine, nimodipine, and nifedipine.
Keywords
lercanidipine; nimodipine; nifedipine; calcium channel blockers
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