Comparing the effect of Leukocyte PRF (L-PRF) and Advanced PRF(A-PRF) added to nanohydroxyapatite on osseous regeneration after maxillary cyst enucleation (Randomized controlled trial) | ||
| Egyptian Journal of Oral and Maxillofacial Surgery | ||
| Volume 15, Issue 2, April 2024, Pages 65-75 PDF (1.38 M) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/OMX.2024.278499.1233 | ||
| Authors | ||
| Areeg Ahmed Elsakka* 1; moustafa Taha2; Yasser Nabil3; mohamed diaa4 | ||
| 1Oral and maxillofacial department,faculty of dentistry,ains hams university,cairo,egypt | ||
| 2Department of oral and maxillofacial surgery, Faculty of dentistry, Ain shams university, Cairo, Egypt | ||
| 3Oral Maxillofacial Surgery, Specialized Dental Military Teaching hospital, Kobry Elkobba complex, Cairo, Egypt | ||
| 4Oral and Maxillofacial department, faculty of Dentistry, Ain Shams University, Cairo, Egypt | ||
| Abstract | ||
| Purpose: To assess the difference between the effect of Leukocyte PRF (L-PRF) and Advanced PRF(A-PRF) added to nano hydroxyapatite bone graft on osseous regeneration after cyst enucleation. Methodology: This clinical study was a Randomized Controlled Trial on 21 patients seeking treatment of maxillary cyst and randomly allocated into 3 groups each group containing 7 patients. In group A, a blood sample was collected for preparation of A-PRF and added to nano hydroxyapatite bone graft to fill the bony defect after cyst enucleation. In group B, L-PRF was prepared and added to nanobone to fill the defect. While group C was a negative control group with no grafting of residual defect. Results: Regarding CT preoperative and postoperative volumetric measurements of the defect, there was a significant difference between different groups (p=0.002). Defect volume was reduced by 80.72% in group A followed by group B which reduced by 62.36% then group C reduced by 21.49 %.Also, there was increase in bone density by 78.56% in group A followed by group B increased by 53.70% while in group C increased by 21.49%.And also, there was 78.64% reduction in size of the residual defect in group A followed by group B reduced by 66.20% and the least group was group C reduced by 48.60%. Conclusion: A-PRF/nanobone mixture accelerated bone healing and improved both quality and quantity of regenerated bone in residual defects compared to L-PRF/ Nanobone mixture and control groups. And outcomes of L-PRF/ Nanobone mixture were better than control group. | ||
| Keywords | ||
| cyst; PRF; L-PRF; A-PRF; Nanobone | ||
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