Is serum vitamin D level is risk factor in pathogenesis of otitis media with effusion | ||
| Aswan University Medical Journal | ||
| Article 19, Volume 4, Issue 1, June 2024, Pages 195-204 PDF (626.66 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/aumj.2024.275206.1107 | ||
| Authors | ||
| Essam AboElmagd1; Mahmoud Khalifa1; Eslam ElNakeeb2; Ismail Mohamed Ibrahim* 1; Dalia Fahim Mohamed Fahim3; Aida A. AbdElmaksod4 | ||
| 1Otorhinology department, faculty of medicine, Aswan University | ||
| 2Clinical pathology department, faculty of medicine, Aswan University | ||
| 3Audiology department, faculty of medicine, Assiut University | ||
| 4Otorhinology department, faculty of medicine, South Valley University | ||
| Abstract | ||
| Background: Otitis media with effusion (OME) is the most common cause of hearing loss in children, its claimed that Vitamine D deficiency may have a role Objectives: to assess the role of vitamin D deficiency in otitis media with effusion. Patients and Methods: this study included 150 children with OME aged 3 to 14 years, Vitamin D level was assessted to all patients compared to Vitamin D level of 50 healthy volunteers. All patients with OME were received medical treatment for two weeks and followed up for three months. Then divided into two groups; A1 (120) respond to medical treatment and A2 (30) not respond to medical treatment. Vitamin D levels were compared to these two subgroups and compared to group B ( healthy volunteers). Results: 135 patients of OME had mild conductive hearing loss , and 15 had moderate conductive hearing loss in comparison to those healthy volunteers with normal hearing with higly statistically significant difference.Both groups of OME had significantly low Vitamin D level in comparison to healthy volunteers.group A1 the mean Vitamine D level was (11.4 ± 9.8) which is significantly higher than that in group A2 (7.1 ± 5.4).Parathyroid hormone (PTH): was 35.8 ± 19.7 in group A1, (47.8 ± 24.7) in group A2 and (47.8 ± 24.7) in group B with highly statistically significant difference. Conclusion: OME patients had significantly lower Vitamin D levels with in comparison with normal volunteers which indicate that supplementation of vitamin D may reduce incidence of OME. | ||
| Keywords | ||
| Vitamin D; OME; PTH | ||
|
Statistics Article View: 157 PDF Download: 164 |
||
