Study of different outcomes and their predictive factors of trans-arterial che-moembolization in patients with hepatocellular carcinoma | ||
| Journal of Current Medical Research and Practice | ||
| Article 3, Volume 9, Issue 2, April 2024, Pages 19-26 PDF (232.62 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/jcmrp.2024.356670 | ||
| Authors | ||
| Rasha Hamed Shehata* 1; Amany Mahran Mohammed Ahmed2; Ehab Fawzy Abdou Moustafa3; Sayed Hassan Ahmed Hassaneen4 | ||
| 1tropical medicine | ||
| 2Department of Tropical Medicine and Gastroenterology, Assiut University, Faculty of Medicine, | ||
| 3Department of Tropical Medicine and Gastroenterology, Assiut University, Faculty of Medicine | ||
| 4Department of Radiodiagnosis, Assiut University, Faculty of Medicine, Assiut University, Assiut, Egypt. | ||
| Abstract | ||
| Abstract Background& aim: Many staging systems were created to categorize patients with hepa-tocellular carcinoma, but none were created, especially to forecast treatment outcomes. The current study evaluated scores for hepatic decompensation prediction following TACE. Patients& methods: Transarterial chemoembolization was performed on 100 patients with hepatocellular cancer for the study. All patients go through a complete clinical eval-uation and history taking. Imaging investigations and baseline and follow-up laboratory data were performed on each patient. IRBno:17101151. Results: Most patients were men in their sixth decade of life. It was discovered that 22% and 78% of patients, respectively, had received non-objective and objective responses. With low-risk ART and a HAP class of C or lower, most patients who experienced an objective response were female. In contrast, according to multivariate regression analysis, the low-risk ART score and HAP score > C were predictors of non-objective response. Conclusion: Various prognostic ratings could be applied to predict hepatic decompensa-tion in TACE patients. Trans arterial chemoembolization was performed on hepatocellu-lar cancer follow-up patients to determine response and post-trans arterial chemoemboli-zation syndrome. Such findings should be confirmed by multicenter trials involving large numbers of patients. | ||
| Keywords | ||
| Hepatic decompensation; hepatocellular malignancy; and transarterial che-moembolisation | ||
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