The Role of serum of Interleukin-6 in Predicting the Development of Meconium Aspiration Syndrome in Infants Born with Meconium-Stained Amniotic Fluid | ||||
Benha Journal of Applied Sciences | ||||
Article 8, Volume 9, Issue 1, January 2024, Page 55-59 PDF (524.52 K) | ||||
Document Type: Original Research Papers | ||||
DOI: 10.21608/bjas.2024.284842.1417 | ||||
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Authors | ||||
Nashwa Farouk Mohamed1; Osama Aboalfotoh Elfeky2; Mostafa Saeed Abdelhamed Zidan ![]() | ||||
1Lecturer of Pediatrics Faculty of Medicine , Benha University | ||||
2Professor of Pediatrics Faculty of Medicine - Benha University | ||||
3Department of Pediatrics Faculty of Medicine - Benha University | ||||
4Lecturer of clinical and chemical pathology Faculty of Medicine , Benha University | ||||
Abstract | ||||
Background: When a baby breaths in a combination of amniotic fluid and meconium shortly after birth, it may cause meconium aspiration syndrome (MAS). Aim and objectives: Evaluation of Interleukin-6 (IL-6) serum levels in infants whose amniotic fluid has been tainted with meconium. Patient and methods: The subjects of this comparative cross-sectional research were 120 full-term infants whose mothers had MSAF. They were split into One group, called the MAS group, consisted of sixty newborns who had meconium aspiration syndrome, whereas the other, called the control group, consisted of sixty neonates who did not have the condition. Results: For Il-6, there was a positive correlation with trauma, newborn pulse, stuff cells, AST, and ALT, and a negative correlation with haemoglobin and PLT. However, for recurrent infection, PROM, foetal distress, labour complications, white blood cells, CRP, urea, creatinine, bilirubin, sodium, potassium, sulphur dioxide, pH, bicarbonate, and carbon dioxide, there was no statistically significant correlation. Conclusion: There was a strong negative link between Il-6 and Haemoglobin and PLT, but a strong positive correlation with neonatal pulse, stuff cells, AST, and ALT. | ||||
Keywords | ||||
IL-6; Meconium maternal chronic illness; Congenital malformations | ||||
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