Correlation between Vitamin D and Glucose Level in Children with Growth Hormone Treatment | ||||
| The Egyptian Journal of Hospital Medicine | ||||
| Article 143, Volume 95, Issue 1, April 2024, Page 2225-2229 PDF (583.07 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/ejhm.2024.360966 | ||||
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| Abstract | ||||
| Background: There is a lack of extensive study investigating the possible connection between vitamin D levels and glucose metabolism in children undergoing growth hormone (GH) treatment. Aim: This research aims to examine the alterations in vitamin D and fasting glucose levels after one year of GH therapy in youngsters. Methods: A longitudinal cohort research tracked a group of 40 youngsters (aged 8-14 years) who required growth hormone (GH) medication due to medical reasons. Prior to commencing treatment, baseline evaluations were performed to measure the levels of vitamin D (in ng/dL) and fasting glucose (in mg/dL). Subsequent evaluations were conducted after one year of uninterrupted growth hormone therapy. Results: Growth hormone therapy decreased vitamin D levels and elevated fasting glucose levels, potentially impacting blood sugar control and insulin sensitivity. Insufficient vitamin D levels can lead to health issues. Conclusion: GH medication affected vitamin D levels and possibly affected glucose homeostasis. These data might contribute to future studies on the impact of vitamin D supplementation in enhancing growth and metabolic well-being in children undergoing GH therapy. Further research is needed to determine the full impact of growth hormone therapy on individual health and other factors. | ||||
| Keywords | ||||
| Vitamin D; Glucose levels; Growth hormone treatment; Children; Longitudinal study | ||||
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