CORRELATION BETWEEN MACULAR AND IRIS AND MACULAR THICKNESS IN CONTROLLED VERSUS UNCONTROLLED DIABETIC PATIENTS | ||
| Egyptian Journal of Clinical Ophthalmology | ||
| Article 9, Volume 7, Issue 1, June 2024, Pages 69-75 PDF (227.38 K) | ||
| Document Type: Original articles: include clinical trials, interventional research, Basic researches and clinically relevant laboratory investigations | ||
| DOI: 10.21608/ejco.2024.361191 | ||
| Authors | ||
| Mohamed, M.; Abdallah, A.; Abdelsadek, A. | ||
| Ophthalmology dept., Faculty of Medicine, Sohag, Univ., Egypt | ||
| Abstract | ||
| Background: Diabetes mellitus (DM) can lead to ocular complications, including diabetic retinopathy (DR) and macular edema. The current research compared iris thickness (IT) and central macular thickness (CMT) between controlled and uncontrolled diabetic patients. Methods: Sixty patients participated in the cross-sectional study, aged ≥18 years with controlled (n=20) and uncontrolled (n=20) DM, and non-diabetic controls (n=20). CMT and IT at1,2, and 3 millimeters from the margin of the pupil were measured using optical coherence tomography (OCT) and anterior segment imaging, respectively. Results: Compared to the control group, both diabetic groups had considerably decreased CMT (p < 0.001), but comparable between controlled and uncontrolled diabetics. There were no discernible variations in IT between the groups regardless of the distance. The results showed that CMT and IT had a significantly negative correlation with diabetics under control at 2 mm (r = -0.569, p = 0.008), but not at other distances. Conclusions: Diabetic patients exhibited macular thinning regardless of glycemic control, while IT was unaffected. Interestingly, lower CMT correlated with reduced IT at specific locations (IT2 and IT3) in controlled diabetics, suggesting a potential relationship between these ocular parameters in this population. | ||
| Keywords | ||
| Diabetes mellitus; Diabetic retinopathy; Macular thickness; Iris thickness; Optical coherence tomography | ||
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