Clinical Impact of COVID-19 Infection on Rheumatoid Arthritis Patients | ||
| Aswan University Medical Journal | ||
| Article 23, Volume 4, Issue 1, June 2024, Pages 232-243 PDF (893.33 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/aumj.2024.296833.1120 | ||
| Authors | ||
| Loay Aglan1; Nihal Fathi2; Sara Sayed Haseib* 1; Fatma Elnoby2 | ||
| 1Rheumatology , Rehabilitation and physical medicine department, Faculty of medicine, Aswan university | ||
| 2Rheumatology , Rehabilitation and physical medicine department, Faculty of medicine, Assiut university | ||
| Abstract | ||
| Background: Rheumatoid arthritis is a chronic autoimmune inflammatory disease that manifests as stiffness, swelling, and pain in the joints, typical of symmetrical polyarthritis. Aim: To study the clinical impact of COVID-19 infection on rheumatoid arthritis patients in Aswan university hospital. Materials and methods: a Retrospective study was carried out in the rheumatology outpatient clinic in Aswan university hospital. 250 RA patients diagnosed according to the 2010 ACR/EULAR classification criteria, Diagnosis of COVID-19 will be made in the patients with clinical manifestations consistent with COVID-19 and meeting one of the following criteria: Positive PCR or Chest CT scans findings of COVID-19 pneumonia. Results : COVID-19 positivity was higher in RA patients who had DM, and also showed a statistically significant increase in DAS 28, Arthralgia, Arthritis, Nervous system and GIT affection and Chest symptoms among the infected group as p-Value <0.05. However, there were no statistical significant difference between the two groups regarding sociodemografic data, lab investigations, radiological investigations and treatment as p-Value <0.05. Conclusion: DM increases the risk of Covid-19 infection in patients with rheumatoid arthritis. It caused reduced juxta-articular osteopenia and greater arthralgia, arthritis, nervous system, GIT, CVS, and chest symptoms with elevated platelet counts. Also, Covid-19 infection results in significant increase in disease activity (DAS 28) in RA patients. | ||
| Keywords | ||
| rheumatoid arthritis; covid-19; clinical impact | ||
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