Platelet-rich plasma versus conventional dressing: does this really affect diabetic foot wound-healing outcomes?
Abd El-Mabood, E., Ali, H. (2018). Platelet-rich plasma versus conventional dressing: does this really affect diabetic foot wound-healing outcomes?. EKB Journal Management System, 37(1), -. doi: 10.4103/ejs.ejs_83_17
El-Sayed A. Abd El-Mabood; Hazem E. Ali. "Platelet-rich plasma versus conventional dressing: does this really affect diabetic foot wound-healing outcomes?". EKB Journal Management System, 37, 1, 2018, -. doi: 10.4103/ejs.ejs_83_17
Abd El-Mabood, E., Ali, H. (2018). 'Platelet-rich plasma versus conventional dressing: does this really affect diabetic foot wound-healing outcomes?', EKB Journal Management System, 37(1), pp. -. doi: 10.4103/ejs.ejs_83_17
Abd El-Mabood, E., Ali, H. Platelet-rich plasma versus conventional dressing: does this really affect diabetic foot wound-healing outcomes?. EKB Journal Management System, 2018; 37(1): -. doi: 10.4103/ejs.ejs_83_17

Platelet-rich plasma versus conventional dressing: does this really affect diabetic foot wound-healing outcomes?

The Egyptian Journal of Surgery
Article 4, Volume 37, Issue 1, January 2018  XML PDF (2.2 MB)
DOI: 10.4103/ejs.ejs_83_17
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Authors
El-Sayed A. Abd El-Mabood; Hazem E. Ali
Abstract
Purpose
This study aimed to compare platelet-rich plasma (PRP) versus conventional ordinary dressing in the management of diabetic foot wounds.
Background
Diabetic foot wound treatment poses a considerable burden on the medical system, with long waiting times for healing in the public hospital system. PRP enables efficient treatment of many patients with hemostatic, anti-inflammatory, and analgesic substances.
Patients and methods
This prospective study was focused on 80 diabetic feet wounds. Patients were divided into two groups: group A received conventional ordinary dressing (=40, 50%) and group B received PRP dressing (=40, 50%). The mean follow-up period was 12 weeks.
Results
The estimated time of wound healing was 12 weeks for 82.5% of the patients in group A and 97.5% of the patients in group B; the PRP group was found to be more effective with fewer complications, less infection, exudates, pain, and failed healing: 17.5, 12.5, 32.5, and 2.5% versus 27.5, 42.5, 62.5, and 17.5% in group B, respectively (=0.001). The highest healing rate was observed for both groups at the fourth week, but it was better for the PRP group (group B): 0.89±0.13 versus 0.49±0.11 cm/week in group A.
Conclusion
There have been considerable advancements in the use of PRP in therapeutic processes in recent years in tissue regeneration therapy. PRP is a powerful tool for the treatment of chronic wounds and very promising for diabetic foot wounds; PRP enables healing, and reduces infection rates and exudates.
Keywords
Conventional Ordinary Dressing; diabetic foot wounds; healing outcomes; platelet-rich plasma
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