Evaluating The Influence of Vitamin E and Selenium on The Uterine Health of Adult Female Goats: A Histological Study | ||
| Egyptian Journal of Veterinary Sciences | ||
| Article 9, Volume 56, Issue 8, August 2025, Pages 1745-1753 PDF (1.16 M) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ejvs.2024.285414.2038 | ||
| Authors | ||
| Alaa Shamil Alalaf* ; Raghad Alnuaimy | ||
| Department of Animal Production , College of Agriculture and forestry , University of Mosul, Mosul, Iraq. | ||
| Abstract | ||
| The uterus is a remarkable organ. with an unmatched ability to grow and regenerate, undergoing continuous cyclic transformations. Vitamins E and selenium renowned for their antioxidant properties and reparative actions in microstructural rehabilitation and repair. Therefore, the current study was conducted to investigate the influence of vitamin E and selenium on the histomorphology of uterine tissue in adult female goats (Capra hircus). Ten healthy animals were used in this study. And divided into two groups. The first group was the control group fed regular diet (standard) and provided water ad libitum. The second group received the same food but with a combination of vitamin E and selenium given 2ml per day in water for 25 days. Uterine samples were collected and preserved in 10% NBF. Routine histological processing was performed and sections were stained with Harries hematoxylin and eosin stain, and Masson's trichrome stain, as well as additional slides were stained with Periodic Acid Schiff (PAS) and Alcian blue 2.5 pH. The observations revealed that vitamin E/selenium supplemented animals had healthier uterine microstructure, since it fixed the epithelial disintegration, uterine glands integrity, and uterine microvasculature, furthermore the supplemented animal had larger caruncles and thicker myometrial musculature, The histochemical findings showed an intense PAS reaction in the uterine epithelium basement membrane, uterine glands, wall of blood vessels. The alcian blue stain showed positive reaction in the endometrium ground substance. Encouragingly, incorporating vitamin E and selenium synergistic supplements holds promise for augmenting animal fertility and increasing conception rates. | ||
| Keywords | ||
| Animal; Histochemical; Goats; Uterus; Vitamin E/Selenium | ||
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