EXPERIMENTAL STUDY ON ANIMAL MODELS TO EVALUATE DIFFERENT MESH MATERIALS FOR INTRAPERITONEAL PROSTHESIS AND DIFFERENT WAYS OF FIXATION BY GLUES AND STAPLES | ||||
The Egyptian Journal of Surgery | ||||
Volume 32, Issue 4, October 2013, Page 293-303 PDF (702.98 K) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/ejsur.2013.366724 | ||||
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Authors | ||||
Stefano Olmi1; Ahmed Talha* 2; Giovanni Cesana1; Alessandro Addis3; Cinzia Domeneghini3 | ||||
1Department of Surgery, Policlinico San Marco, Zingonia-Osio Sotto (BG), Italy | ||||
2Department of Surgery, Policlinico San Marco, Zingonia-Osio Sotto (BG), Italy, 2Department of Surgery, MRI, Alexandria University, Egypt | ||||
3Faculty of Veterinary Medicine, University of Milan, Italy | ||||
Abstract | ||||
Summary Background Data: Feasibility of laparoscopic repair of the abdominal wall defects have been widely documented and showing good characteristics in terms of a reduction of morbidity, postoperative pain, intervention times and hospitalization, a reduction of wound complication and a further reduction of recurrences. Objective: The aim of this study was to determine the best intraperitoneal mesh material and the best fixing device for laparoscopic repair of abdominal wall defects and, secondly, to verify its feasibility and safety. Materials and methods: The tests were carried out on 5 pigs, in accordance with all international laws, ethics, regulations and quality criteria. In each pig we positioned 5 different meshes in each hemi-abdomen (Parietex, Hi-Tex, Proceed, Composix and Goretex) and fixing them with 5 different fixing devices (Tissucol, Glubran, Quixil, EMS and Protack). We carried out a laparoscopic second look at 15 and 30 days, and biopsies were taken for histological analysis and strength tests after pig's suppression. Results: No intra-operative and post-operative complications were observed. The best mesh material resulted to be Parietex, Composix and then Hi-Tex, with the best reperitonalization, no adhesions, no shrinkage, no migration of the mesh and good tensile strength. Histopathological analysis confirmed a greater stability and great tissue integration. Conclusion: This study showed that the best intraperitoneal prosthetic materials for laparoscopic repair of abdominal wall defects were Parietex, Composix and Hi-Tex, with the use of Tissucol and Quixil as fixing devices for the prosthesis. | ||||
Keywords | ||||
Laparoscopic repair; Intraperitoneal prosthesis; Dual mesh; Fixing device; Abdominal wall defect | ||||
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