EXPERIMENTAL STUDY ON ANIMAL MODELS TO EVALUATE DIFFERENT MESH MATERIALS FOR INTRAPERITONEAL PROSTHESIS AND DIFFERENT WAYS OF FIXATION BY GLUES AND STAPLES
Olmi, S., Talha, A., Cesana, G., Addis, A., Domeneghini, C. (2013). EXPERIMENTAL STUDY ON ANIMAL MODELS TO EVALUATE DIFFERENT MESH MATERIALS FOR INTRAPERITONEAL PROSTHESIS AND DIFFERENT WAYS OF FIXATION BY GLUES AND STAPLES. EKB Journal Management System, 32(4), 293-303. doi: 10.21608/ejsur.2013.366724
Stefano Olmi; Ahmed Talha; Giovanni Cesana; Alessandro Addis; Cinzia Domeneghini. "EXPERIMENTAL STUDY ON ANIMAL MODELS TO EVALUATE DIFFERENT MESH MATERIALS FOR INTRAPERITONEAL PROSTHESIS AND DIFFERENT WAYS OF FIXATION BY GLUES AND STAPLES". EKB Journal Management System, 32, 4, 2013, 293-303. doi: 10.21608/ejsur.2013.366724
Olmi, S., Talha, A., Cesana, G., Addis, A., Domeneghini, C. (2013). 'EXPERIMENTAL STUDY ON ANIMAL MODELS TO EVALUATE DIFFERENT MESH MATERIALS FOR INTRAPERITONEAL PROSTHESIS AND DIFFERENT WAYS OF FIXATION BY GLUES AND STAPLES', EKB Journal Management System, 32(4), pp. 293-303. doi: 10.21608/ejsur.2013.366724
Olmi, S., Talha, A., Cesana, G., Addis, A., Domeneghini, C. EXPERIMENTAL STUDY ON ANIMAL MODELS TO EVALUATE DIFFERENT MESH MATERIALS FOR INTRAPERITONEAL PROSTHESIS AND DIFFERENT WAYS OF FIXATION BY GLUES AND STAPLES. EKB Journal Management System, 2013; 32(4): 293-303. doi: 10.21608/ejsur.2013.366724

EXPERIMENTAL STUDY ON ANIMAL MODELS TO EVALUATE DIFFERENT MESH MATERIALS FOR INTRAPERITONEAL PROSTHESIS AND DIFFERENT WAYS OF FIXATION BY GLUES AND STAPLES

The Egyptian Journal of Surgery
Volume 32, Issue 4, October 2013, Pages 293-303    PDF (702.98 K)
Document Type: Original Article
DOI: 10.21608/ejsur.2013.366724
Authors
Stefano Olmi1; Ahmed Talha* 2; Giovanni Cesana1; Alessandro Addis3; Cinzia Domeneghini3
1Department of Surgery, Policlinico San Marco, Zingonia-Osio Sotto (BG), Italy
2Department of Surgery, Policlinico San Marco, Zingonia-Osio Sotto (BG), Italy, 2Department of Surgery, MRI, Alexandria University, Egypt
3Faculty of Veterinary Medicine, University of Milan, Italy
Abstract
Summary Background Data: Feasibility of laparoscopic repair of the abdominal wall defects have been 
widely documented and showing good characteristics in terms of a reduction of morbidity, postoperative 
pain, intervention times and hospitalization, a reduction of wound complication and a further reduction of 
recurrences.
Objective: The aim of this study was to determine the best intraperitoneal mesh material and the best fixing 
device for laparoscopic repair of abdominal wall defects and, secondly, to verify its feasibility and safety.
Materials and methods: The tests were carried out on 5 pigs, in accordance with all international laws, ethics, 
regulations and quality criteria. In each pig we positioned 5 different meshes in each hemi-abdomen (Parietex, 
Hi-Tex, Proceed, Composix and Goretex) and fixing them with 5 different fixing devices (Tissucol, Glubran, 
Quixil, EMS and Protack). We carried out a laparoscopic second look at 15 and 30 days, and biopsies were 
taken for histological analysis and strength tests after pig's suppression.
Results: No intra-operative and post-operative complications were observed. The best mesh material resulted 
to be Parietex, Composix and then Hi-Tex, with the best reperitonalization, no adhesions, no shrinkage, no 
migration of the mesh and good tensile strength. Histopathological analysis confirmed a greater stability and 
great tissue integration.
Conclusion: This study showed that the best intraperitoneal prosthetic materials for laparoscopic repair of 
abdominal wall defects were Parietex, Composix and Hi-Tex, with the use of Tissucol and Quixil as fixing 
devices for the prosthesis.
Keywords
Laparoscopic repair; Intraperitoneal prosthesis; Dual mesh; Fixing device; Abdominal wall defect
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