FEASIBILITY AND OUTCOME OF SURGICAL RESECTION OF HEPATOCELLULAR CARCINOMA | ||||
The Egyptian Journal of Surgery | ||||
Article 2, Volume 31, Issue 1, January 2012, Page 6-11 PDF (528.26 K) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/ejsur.2012.367267 | ||||
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Authors | ||||
Alaa Abdel-Razek* ; Samer Bessa; Mohamed Sharaan | ||||
Department of General Surgery, Faculty of Medicine, Alexandria University | ||||
Abstract | ||||
Introduction: Hepatocellular carcinoma is the fifth most common tumor world-wide. Two- thirds of hepatocellular carcinoma tumors are first diagnosed at advanced stages with consequent dismal prognosis. There are different treatment algorithms. Aim: of this study was to assess the feasibility and outcome of resection of hepatocellular carcinoma tumors. Methods: This study included 215 consecutive patients with hepatocellular carcinoma. Triphasic CT, Child`s classification and intraoperative ultrasonography were used to assess resectability. Resection was done for solitary tumors in Child A or B patients preserving at least 50% of total liver volume. Results: The median age was 58 years. There were 146 males (67.9 %) and 69 females (32.1%). Resection was feasible for 36 (16.7%) patients. Postoperative complications occurred in 8 (22.2%) patients with 1-, 2- and 3- year survival rates 69.4%, 47.2% and 41.6% respectively. Conclusions: Feasibility of hepatic resection was limited for 16.7% patients. By meticulous assessment, resection could be the best treatment for many tumors larger than 5 cm in diameter. Non-anatomical resection was valuable to allow resection of selected tumors with preservation of sufficient liver tissue. There is controversy in feasibility of surgery among algorithms. | ||||
Keywords | ||||
Hepatocellular carcinoma; hepatic resection; intraoperative ultrasonography; nonanatomical resection | ||||
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