The Effect of Honey and Propolis on Oral Mucositis in Patients Undergoing Radiotherapy and Chemotherapy
Ali Amine, P., Hamid Salah Eldin, P., Osama Aboraya, A., AL-Gamal, R. (2024). The Effect of Honey and Propolis on Oral Mucositis in Patients Undergoing Radiotherapy and Chemotherapy. EKB Journal Management System, 10(3), 478-490. doi: 10.21608/jsezu.2024.367472
Prof. Dr. Ahmed Ali Amine; Prof. Dr. Manal Abdel Hamid Salah Eldin; Ass. Prof. Dr. Alaa Osama Aboraya; Raneem Aiman AL-Gamal. "The Effect of Honey and Propolis on Oral Mucositis in Patients Undergoing Radiotherapy and Chemotherapy". EKB Journal Management System, 10, 3, 2024, 478-490. doi: 10.21608/jsezu.2024.367472
Ali Amine, P., Hamid Salah Eldin, P., Osama Aboraya, A., AL-Gamal, R. (2024). 'The Effect of Honey and Propolis on Oral Mucositis in Patients Undergoing Radiotherapy and Chemotherapy', EKB Journal Management System, 10(3), pp. 478-490. doi: 10.21608/jsezu.2024.367472
Ali Amine, P., Hamid Salah Eldin, P., Osama Aboraya, A., AL-Gamal, R. The Effect of Honey and Propolis on Oral Mucositis in Patients Undergoing Radiotherapy and Chemotherapy. EKB Journal Management System, 2024; 10(3): 478-490. doi: 10.21608/jsezu.2024.367472

The Effect of Honey and Propolis on Oral Mucositis in Patients Undergoing Radiotherapy and Chemotherapy

مجلة دراسات وبحوث التربية النوعية
Volume 10, Issue 3 - Serial Number 25, July 2024, Page 478-490  XML PDF (809.29 K)
Document Type: المقالة الأصلية
DOI: 10.21608/jsezu.2024.367472
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Authors
Prof. Dr. Ahmed Ali Amine1; Prof. Dr. Manal Abdel Hamid Salah Eldin2; Ass. Prof. Dr. Alaa Osama Aboraya3; Raneem Aiman AL-Gamal4
1Professor of Nutrition, Nutrition and Food Science Dept., Faculty of Home Economics, Helwan University
2professor of Medical Oncology, Oncology Center, Faculty of Medicine, Mansoura University
3Associated professor of Nutrition,Nutrition and Food Science Dept., Faculty of Home Economics, Helwan University
4B.Sc. In Home Economics, Dietetics program, Nutrition and Food Science Dept. Faculty of Home Economics, Helwan University 2018.Supervisors
Abstract
Background: Oral mucositis (OM) is a common complication in cancer patients receiving radiotherapy or chemotherapy, impacting treatment outcome. Prevention and treatment of OM is an urgent problem in the field of anticancer therapy. This study aimed to evaluate the efficacy of honey with or without propolis in prevention and treatment of OM.
Patients and methods: This study was conducted at the Oncology Center, Mansoura University.  Eighty patients were included and were classified into three groups: First group consisted of 30 patients, received pure natural commercial honey (40 ml divided into 4 times daily); Second group (30 patients), received same amount of honey in addition to propolis (0.5gram) and the third group (control group; 20 patients), only kept oral hygiene, or received anesthetic agents including benzocaine or lidocaine gel. Treatment started on the first day of chemotherapy or radiotherapy and continued for 3 weeks.
Results: Among the whole group of patients, forty-two patients developed OM. There was significant difference in the occurrence of mucositis among groups in favor of patients in both experimental groups (50%, 36.6 % and 80% in groups 1, 2 and 3; respectively). Severe mucositis was lower among patients in the study group (23.1%) compared to the control group (31.3%).
Conclusion: Oral intake of honey is valuable in reducing incidence and severity of oral mucositis compared to oral hygiene. Enrichment with propolis further decreases OM.
Keywords
oral hygiene; lidocaine gel; benzocaine; prevention of mucositis; anticancer therapy
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