Impact of Metabolic Associated Fatty Liver Disease on Health-Related Quality of Life | ||||
| Benha Medical Journal | ||||
| Article 17, Volume 41, Issue 8, December 2024, Page 572-584 PDF (665.37 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/bmfj.2024.289042.2078 | ||||
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| Authors | ||||
Ebada Mohamed Said1; Yaser Mahroos Fouad2; Yousry Esam-Eldin Abo-Amer3; Mohammed Soliman Zidan  4; Alaa El din Ibrahim Kandil5
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| 1Professor of Hepatology, Gastroenterology and Infectious Diseases Faculty of Medicine Benha University | ||||
| 2Professor of Gastroenterology, hepatology and Endemic medicine Faculty of Medicine, Minia University, Minia, Egypt | ||||
| 3Educational Assistant Consultant of Tropical Medicine Mahalla Hepatology Teaching Hospital | ||||
| 4M.B.B.Ch | ||||
| 5Assistant Professor of Hepatology, Gastroenterology, and Infectious Diseases Faculty of Medicine Benha University | ||||
| Abstract | ||||
| Introduction: Metabolic associated fatty liver disease (MAFLD), the nomenclature major benefit is the shift towards a diagnosis of inclusion based on the presence of metabolic dysfunction. MAFLD has also been associated with impaired health-related quality of life (HRQOL). Aim: to assess the impact of MAFLD & degree of hepatic steatosis and fibrosis on patients’ HRQOL applying the SF-36 Questionnaire. Methods: This cross sectional study was carried out on 250 adult who were subdivided into 2 groups, Group I (GI) comprised 150 consecutive patients with MAFLD while Group II (GII) comprised 100 apparently healthy subjects. Both studied groups had completed the short form-36 (SF-36) questionnaire. Results: The mean age among cases group was 43.6 ±10.5 years & females were the predominant. There was a highly statistical significance negative correlation between body mass index (BMI) and all domains of SF-36 questionnaire among GI. Scores of all scales of SF-36 were significantly lower in GI compared to GII). Hepatic steatosis grades with in GI according to CAP values were S1(17.3%), S2(37.3%) and S3(45.3). scores of all scales of SF-36 were significantly lower in S3 patients compared to S2 & S1(P value | ||||
| Keywords | ||||
| Metabolic associated fatty liver disease (MAFLD); Health-related quality of life(HRQOL); Short form-36 (SF-36) questionnaire | ||||
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