Treatment of Male Infertility Using Some Prostaglandin Synthetase Inhibitors | ||
Bulletin of Egyptian Society for Physiological Sciences | ||
Article 2, Volume 28, Issue 1, June 2008, Pages 11-16 PDF (187.13 K) | ||
Document Type: Original Article | ||
DOI: 10.21608/besps.2008.36760 | ||
Authors | ||
Mohamed Ali* 1; M Abdel Mawla2 | ||
1Medical Biochemistry Department, Faculty of Medicine – Zagazig University | ||
2Dermatology Department, Faculty of Medicine – Zagazig University | ||
Abstract | ||
Indomethacin administration at a dose of 25 mg, three times a day for ninety days to a group (n: 20) of oligospermic men caused an increase in sperm count and motility, a higher level of plasma testosterone and a lower seminal prostaglandin E than the corresponding values before drug intake. The pregnancy rate was 15% (3 out of 20). The present result indicates that indomethacin could be helpful in the treatment of some cases of male infertility. | ||
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