Studies on evaluation of inactivated lyophilized Equine Influenza vaccine in Egypt | ||||
| Veterinary Medical Journal (Giza) | ||||
| Volume 57, Issue 3, July 2009, Page 485-495 PDF (2.65 MB) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/vmjg.2011.367865 | ||||
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| Authors | ||||
| M Saad1; Nermin Shafik1; Amal Abdel Hadi1; Nassif A1; Safaa Warda2; Sahar Saber1; Ali M1; Elham El-Ebiary1 | ||||
| 1Central Laboratory for Evaluation of Vet. Biologics, Abbasia, Cairo | ||||
| 2Vet. Serum and Vaccine Research Institute, Abbasia, Cairo | ||||
| Abstract | ||||
| Two batches of egg adapted monovalent inactivated freeze dried equine influenza vaccine (EIV) were evaluated. There was no abnormal appearance of the freezed disc, prepared from locally isolated Strains. The efficacy was tested by lab animal (Guinea pigs) and target animal (horse). The vaccine proved to be safe and potent for both guinea pigs and horses. The mean haemagglutination inhibition (HI) antibodies of the vaccine reconstituted in DEAE-Dextran solution (as a solvent and adjuvant) were 120.4 and 153.7 in G. pigs, 179.2 and 230.4 in horses for the two batches of vaccine respectively. The keeping quality of the local prepared vaccine was studied, Shelf validity was stable at 4°C for one year, could be kept at -20°C for 3 years and 10 months at 40°C. | ||||
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