Evaluation of the Efficacy of Combined Sentinel Lymph Node Biopsy Using Patent Blue Dye and Peripheral Lymph Node Biopsy in Management of Nodal Negative Early Breast Cancer | ||||
| Ain Shams Journal of Surgery | ||||
| Volume 17, Issue 3, July 2024, Page 205-213 PDF (752.39 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/asjs.2024.368113 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
| Mina Ibrahim Ishac Shenouda* ; Mohammed Ahmed Mohammed Khalfallah; Mohammed Hamdy Zeid; Bishoy Refaat Ragheb Ayoub | ||||
| Department of General Surgery, Faculty of Medicine, Ain Shams University, Egypt | ||||
| Abstract | ||||
| Introduction: Sentinel node biopsy is now established as the standard care for women with breast cancer. Its accuracy has been validated through multiple clinical trials but with less morbidities than ALND such as pain, restriction of arm movement and lymphedema. Aim of work: To assess the efficacy of combined SLNB using patent blue dye and PLN sampling in the management of nodal negative early breast cancer. We aimed to avoid the skip metastases phenomenon that occurs with SLN biopsy and to avoid the morbidity associated with ALND. Patients and methods: This prospective study was carried out on 50 females at the Breast Surgery Department in Ain Shams University Hospitals and El Helal Health Insurance Hospital after approval of the ethical committee. Results: In our study, by combining the SLN technique with PLN technique using patent blue dye alone i.e. (without the radioisotope technique) we achieved high accuracy and less false negative rate by simple and cheap method. These techniques when done by an experienced surgeon can be used confidently in patients with early breast cancer. Conclusion: We have found that combining PLN sampling with SLNB makes it possible to avoid ALND in a considerable proportion of breast cancer | ||||
| Keywords | ||||
| Sentinel lymph node; axillary lymph node dissection; peripheral lymph node | ||||
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