Ovarian hyperstimulation syndrome: an overview and prevention approaches
Abdallah, A., Sarhan, H., Hussein, A., Mosbeh, M., Sadek, E. (2024). Ovarian hyperstimulation syndrome: an overview and prevention approaches. EKB Journal Management System, (), 96-107. doi: 10.21608/ueccj.2024.304589.1011
Aya Mohammed Abdallah; Hatem Sarhan; Amal Hussein; Mohammed Mosbeh; Eman Sadek. "Ovarian hyperstimulation syndrome: an overview and prevention approaches". EKB Journal Management System, , , 2024, 96-107. doi: 10.21608/ueccj.2024.304589.1011
Abdallah, A., Sarhan, H., Hussein, A., Mosbeh, M., Sadek, E. (2024). 'Ovarian hyperstimulation syndrome: an overview and prevention approaches', EKB Journal Management System, (), pp. 96-107. doi: 10.21608/ueccj.2024.304589.1011
Abdallah, A., Sarhan, H., Hussein, A., Mosbeh, M., Sadek, E. Ovarian hyperstimulation syndrome: an overview and prevention approaches. EKB Journal Management System, 2024; (): 96-107. doi: 10.21608/ueccj.2024.304589.1011

Ovarian hyperstimulation syndrome: an overview and prevention approaches

Upper Egypt Critical Care Journal
Articles in Press, Accepted Manuscript, Available Online from 20 July 2024  XML PDF (644.77 K)
Document Type: Original Article
DOI: 10.21608/ueccj.2024.304589.1011
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Authors
Aya Mohammed Abdallah email 1; Hatem Sarhan2; Amal Hussein3; Mohammed Mosbeh4; Eman Sadek5
1clinical pharmacy department, faculty of pharmacy, Minia university
2pharmaceutics department, faculty of pharmacy, Minia University
3Pharmaceutics dept, Facult of Pharmacy, Minia Universit
4Obstetrics and Gynecology department, Faculty of Medicine, Minia University
5Clinical Pharmacy Department, Faculty of Pharmacy, Minia University
Abstract
Background
Ovarian hyperstimulation syndrome (OHSS) occurs as a consequence of prompt during the luteal phase of ovulation. The syndrome manifests primarily as ascites and pleural effusion, with pericardial effusion occurring rarely. Severe forms accompanied by electrolyte changes, cardiac, hepatic, renal, and hemodynamic problems linked with increased thromboembolic risk.
Main body
Inflammatory mediators, human chorionic gonadotropin, and vascular endothelial growth factor are all included in the pathophysiology of Ovarian hyperstimulation syndrome. Many risk factors affect the syndrome such as body weight, polycystic ovary syndrome, previous OHSS, estradiol level, etc. There are primary and secondary prevention methods to reduce the occurrence of the syndrome.
Conclusion
In GnRH antagonist cycles, gonadotropin-releasing hormone (GnRH) agonist trigger & GnRH agonist triggering have been identified as the most efficient measures for OHSS prevention. Coadministration of dopaminergic agonist & mild ovarian stimulation was demonstrated to be safe & efficacious.
Keywords: Ovarian hyperstimulation, Human chorionic gonadotropin, GnRH agonist, GnRH antagonist, and Estradiol.
Keywords
Ovarian hyperstimulation; Human chorionic gonadotropin; GnRH agonist; GnRH antagonist; and Estradiol
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