Effect of a Mycobacterium extract as an immunomodulator with necrotic enteritis gel vaccine in chicken | ||||
| Veterinary Medical Journal (Giza) | ||||
| Volume 59, Issue 3, July 2011, Page 99-107 PDF (1.38 MB) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/vmjg.2011.368234 | ||||
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| Authors | ||||
| EL-Meneisy A* 1; Nasr A2; Kamal E2 | ||||
| 1Veterinary Serum and Vaccine Research Institute, Abbasia, Cairo, Egypt | ||||
| 2Veterinary Serum and Vaccine Research Institute, Abbasia, Cairo, Egypt. | ||||
| Abstract | ||||
| This study was carried out to assessment the immune response of broiler chickens orally administered Mycobacterium phlei extract as a non-specific immunomodulator prior to vaccination with necrotic enteritis Alhydrogel vaccine. The obtained results cleared that chickens administered M. phlei extract and vaccinated with necrotic enteritis vaccine showed an enhancement in their humoral immune response expressed in a higher alpha antitoxin titers (4 IU/ml) by using serum neutralization test, as well as, an enhancement in their cellular immune response at a higher stimulation index of peripheral blood lymphocytes (PBL) by using lymphocytes proliferation test more than those chickens received necrotic enteritis gel vaccine only. In conclusion M. phei could be used as Immunoenhancer before vaccination in chickens. | ||||
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