Clinico-pathological and Epidemiological Characteristics of Colorectal Cancer Patients - Retrospective Study | ||
| SECI Oncology Journal | ||
| Volume 12, Issue 3, July 2024, Pages 215-219 | ||
| Abstract | ||
| Objective: Our aim of this study was analysis of the clinic epidemiological patterns of colorectal cancer (CRC) in patients presented at clinical oncology department in Assiut university hospitals from 2010 to 2020 Methods: This study included 263 patients with CRC who fulfilled the following criteria: age > 18 years, proven by histopathology, patients with all stages of CRC were included. Data analyses were performed using statistical package for the social science (IBM-SPSS) version 26.0 software. Qualitative data were expressed as frequency and percentage. Mean ± SD was used to express the numerical variables. Results: The mean age of the enrolled patients was 45.88±15.23 years. The incidence was higher in males, accounting for 141 cases (53.6%). the majority, comprising 151 (57.4%), individuals were diagnosed with cancer rectum 66 (25.1%). The most common presenting symptom was constipation 121 (46.0%). The predominant subtype was adenocarcinoma, observed in 186 (70.7%) patients. As for TNM staging the distribution of "T" stages revealed 133 (50.6%) patients at "T3" followed by 65 (24.7%) patients at "T4". Concerning metastasis, 93 (35.4%) patients were diagnosed with synchronous metastasis "M1", while 170 (64.6%) patients were categorized as "M0" Relapse, either distant or local, occurred in 42 (16.0%) patients. Distant relapse was observed in 33 (12.5%) patients. Local relapse occurred in 17 (6.5%) patients. Conclusion: CRC mostly presented at advanced stages so analysis of its risk factors needs further studies to understand its behavior and early detection carry hope for improving its survival. | ||
| Keywords | ||
| colorectal cancer; Epidemiological; Clinico-pathological characteristics | ||
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