TRIAL FOR PREPARATION AND EVALUATION OF LIVE ATTENUATED COMBINED AVIAN ENCEPHALOMYELITIS AND FOWL POX VACCINE IN COMPARISON WITH IMPORTED ONE N.A | ||||
Veterinary Medical Journal (Giza) | ||||
Volume 50, Issue 4, October 2002, Page 1011-1019 PDF (2.37 MB) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/vmjg.2002.369380 | ||||
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Authors | ||||
N SHERIF* 1; ELHAM EL-EBIARY1; SOAD SOLIMAN2; A MICHAEL3; LAMIAA OMAR3; HALA EL-MAKAKY2 | ||||
1Central Laboratory for Control of Veterinary Biologics, Abbasia, Cairo. | ||||
2Veterinary Serum and Vaccine Research Institute, Abbasia, Cairo. | ||||
3Central Laboratory for Control of Veterinary Biologics, Abbasia, Cairo | ||||
Abstract | ||||
An experimental trial was carried out to prepare a combined attenuated vaccine against avian encephalomyelitis (AE) and fowl pox diseases. Monovalent live attenuated vaccine was firstly prepared against each disease on specific pathogen free (SPF) eggs. After titration, they were mixed together and lyophilized as a bivalent live Vaccine. Chickens were vaccinated with the locally prepared vaccine as well as the Imported one. Humoral immune response of the vaccinated chicks was evaluated by using enzyme linked immunosorbent assay (ELISA) for avian encephalomyelitis” was proposed by Van Roekel et al. lomyelitis and neutralization test (NT) for AE and fowl pox viruses. The prepared combined vaccine was found potent, safe and protective against challenge viruses. | ||||
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