Serum irisin with metabolic syndrome, type II diabetes, and insulin resistance | ||||
| Journal of Current Medical Research and Practice | ||||
| Volume 6, Issue 3, July 2021, Page 318-323 PDF (498.54 K) | ||||
| DOI: 10.4103/JCMRP.JCMRP_128_19 | ||||
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| Authors | ||||
| B Osama; S. Osman; Omnia A. El -Moneum Mohamed; Esraa M. Ahmed | ||||
| Abstract | ||||
| Background Obesity is the most significant problem nowadays and is concomitant with higher risk of insulin resistance, type II diabetes, and metabolic syndrome (MetS). Aim The aim of the study was to determine the possible association between serum irisin among obesity-associated MetS and type II diabetes mellitus patients and if there was a connection between serum irisin and insulin resistance. Materials and methods This study was directed on 60 patients '35 patients with MetS and 25 patients with type II diabetes' and 25 healthy controls. Serum irisin was measured by the enzyme-linked immunosorbent assay (ELISA) kits. Results Serum irisin was statistically significantly lower in the MetS group and the DM group in contrast to the control group and also there was significant reduction of the mean value of serum irisin of the MetS group when equated to the DM group. Conclusion In conclusion, this study has shown that there may be an association with decreased irisin level and obesity with insulin resistance. | ||||
| Keywords | ||||
| Metabolic syndrome (MetS); Diabetes mellitus (DM); Irisin | ||||
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