Gastric signet ring cell adenocarcinoma associated with Menetrier’s disease: a rare North African female case report | ||
| African Journal of Gastroenterology and Hepatology | ||
| Volume 7, Issue 1, 2024, Pages 185-196 PDF (719.85 K) | ||
| Document Type: Case Reports | ||
| DOI: 10.21608/ajgh.2024.291022.1054 | ||
| Authors | ||
| Houria Belkralladi1; Zakaria Merad1; Feriel Sellam* 2; Abdelnacer Tou1 | ||
| 1Department of Pathology, Sidi Bel Abbes University Hospital. Faculty of Medicine, Djilali Liabes University, Algeria. | ||
| 2Laboratory of genetic diagnosis and microscopy platform, Biotechnology and Health Division, National Biotechnology Research Center, Constantine, Algeria. | ||
| Abstract | ||
| Background Menetrier's disease is an uncommon disease characterized by diffuse hypertrophy of gastric mucosa and giant gastric rugae with an increased risk of gastric cancer. Only a few reports supporting its association with gastric cancer have been found. Material and methods We present the case of signet ring cell adenocarcinoma associated with Menetrier's disease. The patient is a 54-year-old Algerian female. Results A 54-year-old woman was admitted to our hospital with a history of anemia, anorexia, and 10 kg weight loss. During her hospitalization, the patient presented an extradural hematoma. A biopsy was performed, which revealed a bone metastasis of the carcinomatous process. Abdominal computed tomography demonstrated diffuse thickening of the gastric wall. A gastric biopsy specimen showed thickened gastric mucosa and cystic dilatation of glands compatible with Menetrier's disease and diffuse infiltration by signet ring cell adenocarcinoma. A total gastrectomy was performed. Conclusion A patient with signet ring cell adenocarcinoma associated with Menetrier's disease is reported in our case study. | ||
| Keywords | ||
| Menetrier's disease; signet ring cell adenocarcinoma; gastrectomy; gastric cancer; woman | ||
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