Bacterial Infection profile and Antibiotic sensitivity of Diabetic Foot Ulcer in Zefta Hospitals, Egypt | ||||
Journal of Basic and Environmental Sciences | ||||
Volume 10, Issue 2, April 2023, Page 67-74 PDF (344.79 K) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/jbes.2023.372258 | ||||
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Authors | ||||
Abdelgyed M. Lela; Moataz H. El-Sehrawy; Mohamed A. Abdel-Rahman; Amr A. El-Waseif* | ||||
Botany and Microbiology Dept., Faculty of Science (Boys), Al-Azhar University, Cairo, Egypt | ||||
Abstract | ||||
One of the cause’s insulin patients are sent to clinics is diabetic foot ulcers (DFU), and when this happens, empirical antibiotic therapy is required. In order to evaluate the bacteriological profile and susceptibility pattern of these infections, we undertook a retrospective study of patients with DFU who needed hospitalization. We evaluated 100 patients were collected over a period of 5 months starting from October, 2018 until March 2019 on patients attending the outpatient clinic of diabetic foot unit, Zefta Hospitals, Gharbay, Egypt. The bacteria were isolated from different age, from 62 male there age ranged from 45 to 70 years and from 38 female there age ranged from 40 to 65 years. Gram-positive bacteria were responsible for 52.8% of the isolates, while Gram-negative were responsible for 47.2%. Staphylococcus aureus was the most prevalent pathogen, followed by Escherichia coli. Regarding the susceptibility profile, we found all bacterial strains were sensitive to IPM, except Pseudomonas aureginosa was resistant. IPM was the effective antibiotics against all Gram positive bacteria. All isolates of P. aeruginosa resistant to IPM and susceptible to antibiotics AK, CN. Our result shows S. aureus was susceptible to antibiotics AK, IPM with 100%. The E. coli was susceptible to antibiotics IPM with 100%. Information of microbiological profile and antibiotics susceptibility of patients with DFU is useful to evidence clinical therapy. | ||||
Keywords | ||||
Bacterial infection; Antibiotics resistance; Sensitivity; Diabetic foot ulcers | ||||
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