THORACOSCOPIC SPLANCHNICECTOMY FOR PAIN CONTROL IN IRRESECTABLE PANCREATIC CANCER | ||||
The Egyptian Journal of Surgery | ||||
Volume 26, Issue 1, January 2007, Page 12-16 PDF (183.46 K) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/ejsur.2007.372327 | ||||
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Authors | ||||
Khaled Katri* 1; Bassem Ramadan2; Fath Alla Sidkey3 | ||||
1Department of General Surgery, Faculty of Medicine, Alexandria University | ||||
2Department of Cardiothoracic Surgery, Faculty of Medicine, Alexandria University | ||||
3Department of Internal Medicine, Faculty of Medicine, Alexandria University | ||||
Abstract | ||||
Aim: Disabling pain for many patients with irresectable pancreatic cancer is poorly managed and can remain a significant problem until their deaths. The aim of this study was to evaluate the safety and efficacy of thoracoscopic splanchnicectomy for pain control in patients with irresectable pancreatic cancer. Methods: Thirteen patients suffering from intractable pain due to irresectable pancreatic cancer underwent 15 attempted thoracoscopic splanchnicectomy procedures. All patients were opiate dependent. Right-sided splanchnicectomy was performed for a dominantly right-sided pain, whereas a centralized, bilateral, or left-sided pain was managed by left splanchnicectomy. If pain recurred, patients were offered to have the procedure repeated on the contralateral side. Results: Thoracoscopic splanchnicectomy procedure was a technical failure because of pleural adhesions in one patient. Fourteen (10 left- and 4 right-sided) thoracoscopic splanchnicectomies were successfully completed in 12 patients. Immediate pain relief was achieved in all 12 patients after unilateral thoracoscopic splanchnicectomy. Pain relief persisted till death in 8 patients and till latest postoperative follow-up visit at 5 months in one patient. Two patients required a contralateral procedure for pain recurrence. A third patient had a recurrent pain but refused contralateral intervention. Except the latter, none of the patients required opioids. Conclusion: Thoracoscopic splanchnicectomy is a safe, simple, and effective minimally invasive procedure. It offers a substantial relief of pain in patients with unresectable pancreatic cancer. | ||||
Keywords | ||||
pain management; sympathetic denervation; splanchnic nerves | ||||
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