HUMORAL AND LOCAL IMMUNE RESPONSE TO DIFFERENT NEWCASTLE DISEASE VACCINES
S, M., T, M., HASSANS, N., H, K., EL-ASSILE, S., KHASHABAH, E., EL-BORDINY, F., HADI, A., I, R. (1992). HUMORAL AND LOCAL IMMUNE RESPONSE TO DIFFERENT NEWCASTLE DISEASE VACCINES. EKB Journal Management System, 40(3), 111-118. doi: 10.21608/vmjg.1992.372631
MADKOUR S; MOHAMED T; NADIA HASSANS; KHOUDIR H; SALWA EL-ASSILE; ENSAF KHASHABAH; FEK- RIA EL-BORDINY; AFAF HADI; REDA I. "HUMORAL AND LOCAL IMMUNE RESPONSE TO DIFFERENT NEWCASTLE DISEASE VACCINES". EKB Journal Management System, 40, 3, 1992, 111-118. doi: 10.21608/vmjg.1992.372631
S, M., T, M., HASSANS, N., H, K., EL-ASSILE, S., KHASHABAH, E., EL-BORDINY, F., HADI, A., I, R. (1992). 'HUMORAL AND LOCAL IMMUNE RESPONSE TO DIFFERENT NEWCASTLE DISEASE VACCINES', EKB Journal Management System, 40(3), pp. 111-118. doi: 10.21608/vmjg.1992.372631
S, M., T, M., HASSANS, N., H, K., EL-ASSILE, S., KHASHABAH, E., EL-BORDINY, F., HADI, A., I, R. HUMORAL AND LOCAL IMMUNE RESPONSE TO DIFFERENT NEWCASTLE DISEASE VACCINES. EKB Journal Management System, 1992; 40(3): 111-118. doi: 10.21608/vmjg.1992.372631

HUMORAL AND LOCAL IMMUNE RESPONSE TO DIFFERENT NEWCASTLE DISEASE VACCINES

Veterinary Medical Journal (Giza)
Volume 40, Issue 3, July 1992, Page 111-118  XML PDF (2.47 MB)
Document Type: Original Article
DOI: 10.21608/vmjg.1992.372631
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Authors
MADKOUR S1; MOHAMED T2; NADIA HASSANS1; KHOUDIR H1; SALWA EL-ASSILE1; ENSAF KHASHABAH1; FEK- RIA EL-BORDINY1; AFAF HADI1; REDA I1
1Vet. Scrum & Vaccine Research Inst., Abbassia, Cairo.
2Faculty of Veterinary Medicine, Cairo University.
Abstract
This study was planned to assess the use of highly immunogenic vaccine. Comparing between live and killed ND vaccine and between two types of killed vaccine were used: HB) live NDV vaccine, inactivated aluminum hydroxide gel formalized ND vaccine and inactivated oil ND vaccine. 210 one day old chicks having maternal immunity of mean HI titer 5.5 log were subjected to vaccination with the mentioned ND vaccines and the following results were obtained:

The humoral immune response in chicks after vaccination with live vaccine alone resulted in higher mean HI titer (2.375 log? in 6th week post vaccination) than the use of killed vaccine alone. Inactivated oil emulsion ND vaccine alone induced higher level of humoral HI antibodies titer (1.75 log. in 6th week post Vaccination) than aluminum hydroxide gel formalized ND vaccine alone (1.5 log, in 6th week post vaccination). Also, the use of both live with oil vaccine produced higher humoral immune response (4.5 logy in 6th week post vaccination) than the use of live with aluminum hydroxide vaccine (3.5 log, in 6th week post vaccine.
Study of the local immunity in vaccinated chicks for all groups revealed that these chicks have no local immunity.
The challenge test applied 6 weeks post vaccination indicated that the protection percent was 50%, 62.5%, 87.5%,100% and 80% for the aluminum hydroxide vaccine, oil vaccine, aluminum hydroxide vaccine with live vaccine, oil vaccine with live vaccine and liver vaccine alone respectively.
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