CONTROVERSIES IN THE SURGICAL THERAPY OF DIFFERENTIATED THYROID CARCINOMA: A REPLICATION STUDY REVIEWING 32 CASES | ||||
| The Egyptian Journal of Surgery | ||||
| Volume 23, Issue 4, October 2004, Page 359-365 PDF (153.67 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/ejsur.2004.373736 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
| Alaa M. El-Erian* 1; Reda Saad2; Maher Fathy1 | ||||
| 1Department of surgery, teaching institutes & hospitals | ||||
| 2Department of surgery, Ain shams University | ||||
| Abstract | ||||
| Objective: reevaluation of experience with total versus near total thyroidectomy(TT)in treatment of differentiated thyroid carcinoma. Design: 32 cases of differentiated thyroid carcinoma(21 papillary and 11 follicular) were allocated to receive either total thyroidectomy TT or near total thyroidectomy(NTT)from 1994 through 1997. In TT group, thyroid bed biopsies were taken intraoperatively and the postoperative RAI131 study was assessed to evaluate thoroghness of TT, also extensive histopathologc examination of the contralateral lobe was done to detect multicentric foci. Patients were followed up clinically, biochemically and radiologically to detect complications and recurrences. Results: In TT group, 15of16 cases(93.8%)showed residual uptake in the neck. Also thyroid bed biopsies revealed thyroid tissue in 12(75%), and contralateral lobe revealed cancerous foci in 6(37.5%). 4 of TT group(25%)developed permanent hypoparathyroidism and one developed permanent RLN palsy. In NTT group one developed transient hypoparathyroidism and one developed RLN palsy. 7 cases(20.8%)developed recurrences, 3 in TT group and 4 in NTT group. And 5(15.6%)have died during follow up period, 2 in TT group and 3 in NTT group, all were follicular carcinomas. All cases with papillary carcinoma are still alive. Conclusion: TT Vs NTT appear to bear no significant difference regarding recurrences and overall survival, despite an increased rate of complications in case of TT. | ||||
| Keywords | ||||
| Total thyroidectomy; Near total thyroidectomy; Radioactive iodine; Recurrent laryngeal nerve | ||||
|
Statistics Article View: 55 PDF Download: 28 |
||||
