Bioactive secondary metabolites from marine actinomycetes and their inhibitory effect on bacteria of Drinking water | ||||
| Journal of Basic and Environmental Sciences | ||||
| Volume 11, Issue 1, January 2024, Page 60-70 PDF (513.04 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/jbes.2024.374444 | ||||
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| Authors | ||||
| Mohamed E. Elawady1; Mervat G. Hassan* 2; Ahmed A. Hamed3; Hatem E. Elbeih2; Soheir S. Abdelsalam2 | ||||
| 1Microbial Biotechnology Department, National Research Centre, El- Buhouth Street, Dokki, Cairo, Egypt. | ||||
| 2Microbiology Department, Faculty of Science, Benha University, Benha, Egypt. | ||||
| 3Microbial Chemistry Department, National Research Centre, El-Buhouth Street, Dokki, Cairo, Egypt. | ||||
| Abstract | ||||
| This study focuses on the isolation of marine actinomycetes, their cultivation through fermentation on rice medium, and the subsequent evaluation of their antimicrobial activity. Marine environments are known to harbor diverse and potentially valuable microorganisms, including actinomycetes, which are renowned for their capacity to produce bioactive compounds. Marine actinomycetes were isolated from marine samples, and their cultivation was carried out using a rice-based medium. This fermentation process aimed to stimulate the production of biologically active secondary metabolites. These metabolites are of Journal of Basic and Environmental Sciences 11 (2024) 60-70 -61- particular interest due to their potential antimicrobial properties, which could have significant applications in the field of medicine and biotechnology. The isolated actinomycetes' rice medium extracts were carefully examined for their antimicrobial activity. The study assessed their effectiveness in inhibiting the growth of various microorganisms, highlighting their potential as a source of novel bioactive compounds with applications in the field of antimicrobial agents. The results of this investigation contribute to our understanding of the bioresources present in marine ecosystems and their potential for developing new therapeutic agents. | ||||
| Keywords | ||||
| Antimicrobial activity; Secondary metabolites; Actinomycetes; Streptomyces | ||||
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