A COMPARATIVE STUDY OF CHANGES IN IMMUNOGLOBULINS LEVELS IN PATIENTS WTH IDDM 1 AND NIDDM 2 TYPES OF DIABETES | ||
Journal of Basic and Environmental Sciences | ||
Volume 11, Issue 1, January 2024, Pages 112-123 PDF (890.03 K) | ||
Document Type: Original Article | ||
DOI: 10.21608/jbes.2024.374447 | ||
Authors | ||
Nihad M Alshmary1; Azza M. Marei2; Mohamed N Seddek2 | ||
1Department of Biological Sciences, Clinical Immunology Branch, Mustansiriya University | ||
2Department of Zoology, Faculty of Science Benha University | ||
Abstract | ||
Diabetes mellitus (DM) is defined as a disease that results from an increase in the level of glucose in the blood (Hyperglycemia) over the normal level as a result of lack or reduction of insulin hormone secretion (from the beta cells of islets of Langerhans located within the pancreas) of most vertebrates. Also, it occurs if there is a weakness in the insulin mechanism of action, or both together. In addition, the defect in the Insulin receptors as a result of epidemiological genetic disorders. Diabetes mellitus is caused as a result of the deficiency of β cells in the pancreas, so the production of insulin by these cells is either little or no, and this is known as Type 1 diabetes mellitus insulin-dependent diabetes mellitus (IDDM 1). The body's use of insulin correctly (insulin resistance) is known as type 2 diabetes mellitus noninsulin-dependent diabetes mellitus (NIDDM 2). The work aims to Evaluate some immunological indicators and knowledge of the immunological effects of type 1 diabetics and knowledge of the relationship of age, sex, and duration of disease for patients. | ||
Keywords | ||
Diabetes Mellitus; Immunology; type 2 Diabetes and Immunoglobins | ||
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