EVALUATION OF AUTOLOGOUS FIBRIN GLUE IN MANAGEMENT OF TRAUMATIC LIVER AND SPLENIC INJURIES | ||
| The Egyptian Journal of Surgery | ||
| Volume 21, Issue 4, October 2002, Pages 1103-1113 PDF (477.41 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ejsur.2002.375152 | ||
| Authors | ||
| Sherif Z.M. Kotb* ; Saleh El-Awadi; Tarek Badrawy | ||
| General Surgery Department - Mansoura Faculty of Medicine, Mansoura University. | ||
| Abstract | ||
| A lot of literatures have insisted upon strict preservation of hepatic and splenic tissues in repair of their traumatic injuries. Among several procedures fibrin glue has been described as a topical haemostatic and sealant agent for traumatic hepatic and / or splenic injuries. The aims of the present study were [1] Assessment of the efficacy of autologous fibrin glue in the treatment of traumatic liver and splenic injuries. [2] Comparing fibrin glue therapy with conventional surgical methods. 55 patients, suffered from mild to moderate degrees of internal haemorrhage due to hepatic and/ or splenic injuries, were enrolled in the study. They were considered to be 60 cases, as 5 patients from them suffered from both liver and splenic injuries. They were divided into two groups: [1] Group I: included 32 cases of traumatic liver injury. They were classified into two subgroups: [A] Subgroup A: included 16 cases who were treated with fibrin glue application, and [B] Subgroup B: included 16 cases who were treated with conventional surgical methods. [2] Group II: included 28 cases of traumatic splenic injury. They were also classified into two subgroups: [A] Subgroup A: included 14 cases who were treated with fibrin glue application, and [B] Subgroup B: included 14 cases who were treated with conventional spleen - preserving surgery. The study revealed that: in all patients treated with autologous fibrin glue, there was no post-operative evidence of bleeding from the splenic or hepatic sites after autologous fibrin glue application by examination of the drains. Abdominal ultrasound examination showed no intraperitoneal haemorrhage or subphrenic collection. Examination of the hepatic and splenic sites by CT scanning revealed complete sealing of the fissures and the raw areas in liver and spleen within 2 to 3 weeks. So we can conclude that: fibrin sealing is feasible, effective and safe as conventional surgery for liver and splenic injuries. | ||
| Keywords | ||
| Fibrin glue; Liver trauma; Splenic trauma; Splenorrhaphy | ||
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