EFFECT OF SYNANTHIC AND IVOMEC ON TRICHINELLA SPIRALIS WITH REFERENCE TO THEIR SEROLOGICAL EVALUATION | ||
| Veterinary Medical Journal (Giza) | ||
| Volume 43, Issue 1, January 1995, Pages 31-35 PDF (2.95 M) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/vmjg.1995.375649 | ||
| Authors | ||
| H OMAR* 1; THORAYA EL-ASSALY2; AZIZA AMER3; MONA EL-ENBAAWY4 | ||
| 1Dept. Parasitology | ||
| 2Dept. Parasitology, Animal Health Research Inst. Dokki, Giza | ||
| 3Dept. Pharmacology, Fac. Vet. Med., Cairo University | ||
| 4Dept. Bacteriology, Immunology and Mycology, Fac. Vet. Med., Cairo | ||
| Abstract | ||
| Three groups, each of 10 rats were experimentally infected with Trichinella spiralis larvae (250/rat). On the 5th week postinfection animals of two groups were treated with a single dose of Synanthic (Oxfendazole) and Ivomec MK-933 at a dose of 5 mg and 0.2 mg/kg B. W. respectively. Efficacy rate of the former was 84.2% and for the later was 73.5% depending on the number of living larvae in the diaphragm. Anti-Trichinella spiralis haemagglutinating antibodies were monitored before and after treatment. They were markedly declined two weeks after treatment. This makes passive haemagglutination test a feasible test to evaluate the drug efficacies either in laboratory or field studies. | ||
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