EFFECT OF SYNANTHIC AND IVOMEC ON TRICHINELLA SPIRALIS WITH REFERENCE TO THEIR SEROLOGICAL EVALUATION | ||||
Veterinary Medical Journal (Giza) | ||||
Volume 43, Issue 1, January 1995, Page 31-35 PDF (2.95 MB) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/vmjg.1995.375649 | ||||
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Authors | ||||
H OMAR* 1; THORAYA EL-ASSALY2; AZIZA AMER3; MONA EL-ENBAAWY4 | ||||
1Dept. Parasitology | ||||
2Dept. Parasitology, Animal Health Research Inst. Dokki, Giza | ||||
3Dept. Pharmacology, Fac. Vet. Med., Cairo University | ||||
4Dept. Bacteriology, Immunology and Mycology, Fac. Vet. Med., Cairo | ||||
Abstract | ||||
Three groups, each of 10 rats were experimentally infected with Trichinella spiralis larvae (250/rat). On the 5th week postinfection animals of two groups were treated with a single dose of Synanthic (Oxfendazole) and Ivomec MK-933 at a dose of 5 mg and 0.2 mg/kg B. W. respectively. Efficacy rate of the former was 84.2% and for the later was 73.5% depending on the number of living larvae in the diaphragm. Anti-Trichinella spiralis haemagglutinating antibodies were monitored before and after treatment. They were markedly declined two weeks after treatment. This makes passive haemagglutination test a feasible test to evaluate the drug efficacies either in laboratory or field studies. | ||||
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