STUDIES OF DIFFERENT ADJUVANTS ON THE IMMUNE RESPONSE OF SHEEP TO RIFTVALLEYFEVER | ||||
| Veterinary Medical Journal (Giza) | ||||
| Volume 46, Issue 4, October 1998, Page 719-727 PDF (3.43 MB) | ||||
| DOI: 10.21608/vmjg.1998.377366 | ||||
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| Authors | ||||
| MARCOSS T.N* ; LILY, S. SALAMA; ELIAN, K ALY | ||||
| Veterinary Serum and Vaccine Research Institute , Abbasia ,Cairo. | ||||
| Abstract | ||||
| In this work , two types of Rift Valley Fever (RVF) vaccine were prepared, the first contain 0.5% saponin while the second contained 25 % pure peanut oil . Twelve sheep were divided into four groups, first group (G1) was vaccinated with binary inactivated RVF vaccine with 0.5% saponin, the second group (G2) was vaccinated with binary inactivated RVF vaccine with 25% peanut oil the third group (G3) was vaccinated binary inactivated RVF vaccine with 50% aluminium hydroxide gel while the fourth group (G4) left as a control (non vaccinated ) . All four groups were challenged test with virulent RVF virus. The results revealed that the best vaccine is RVF vaccine containing peanut oil where EDso equal 0.008/100 ml and gave a higher level of antibody all over the period of the test compared with that of other Vaccinated groups when tested by SNT and ELISA tests. | ||||
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