STUDIES ON THE IMMUNE-RESPONSE POST VACCINATION WITH INACTIVATED TISSUE CULTURE RABIES VACCINE | ||||
| Veterinary Medical Journal (Giza) | ||||
| Volume 46, Issue 4, October 1998, Page 743-749 PDF (1.76 MB) | ||||
| DOI: 10.21608/vmjg.1998.377369 | ||||
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| Authors | ||||
| S.M. EDRIES* ; A.M. KOTB; Y.Z. HABASHI | ||||
| Vet. Ser. Vac. Res. Inst., Abbassia, Cairo | ||||
| Abstract | ||||
| The present work was planed to study the immune response of Egyptian dogs to the recently prepared inactivated tissue culture rabies vaccine. Ten dogs of different ages (puppies and adults) were vaccinated with the prepared vaccine at the field dose. All animals showed a detectable titer of rabies antibodies in their sera from the first week post vaccination, reached its peak by the 4th week in adults and 6th week in puppies. All vaccinated dogs remained healthy without showing any abnormal clinical signs all over the experimental period. Also, these animals had a Protective level of antibodies up to about yearPost vaccination. Control contact dogs did not show any signs of illness and remained seronegative. The results of serum neutralization test (SNT) and enzyme linked immunosorbant assay (ELISA) were found to be parallel to each other. So, the inactivated tissue culture rabies vaccine can be considered a safe and potent vaccine to protect dogs against rabies virus infection, simple in its preparation and economic. | ||||
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