The rate and predictors of amenorrhea at 1 year follow up in women using etonogestrel implant
Ali, M., Mohamed, H., Abdel-nazeer, A., Abdelkader, A. (2024). The rate and predictors of amenorrhea at 1 year follow up in women using etonogestrel implant. EKB Journal Management System, 28(4), 3-13. doi: 10.21608/egyfs.2024.378188
Mohammed K. Ali; Hazem S. Mohamed; Ahmed M. Abdel-nazeer; Abdelrahman Mahmoud Abdelkader. "The rate and predictors of amenorrhea at 1 year follow up in women using etonogestrel implant". EKB Journal Management System, 28, 4, 2024, 3-13. doi: 10.21608/egyfs.2024.378188
Ali, M., Mohamed, H., Abdel-nazeer, A., Abdelkader, A. (2024). 'The rate and predictors of amenorrhea at 1 year follow up in women using etonogestrel implant', EKB Journal Management System, 28(4), pp. 3-13. doi: 10.21608/egyfs.2024.378188
Ali, M., Mohamed, H., Abdel-nazeer, A., Abdelkader, A. The rate and predictors of amenorrhea at 1 year follow up in women using etonogestrel implant. EKB Journal Management System, 2024; 28(4): 3-13. doi: 10.21608/egyfs.2024.378188

The rate and predictors of amenorrhea at 1 year follow up in women using etonogestrel implant

The Egyptian Journal of Fertility and Sterility
Article 2, Volume 28, Issue 4 - Serial Number 11106352, July 2024, Page 3-13  XML PDF (3.82 MB)
Document Type: Original Article
DOI: 10.21608/egyfs.2024.378188
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Authors
Mohammed K. Ali1; Hazem S. Mohamed1; Ahmed M. Abdel-nazeer2; Abdelrahman Mahmoud Abdelkader email 3
1Department of Obstetrics and Gynecology, the Faculty of Medicine, Assiut University, Egypt
2Department of Obstetrics and Gynecology, The Dairut Central Hospital, Assiut, Egypt
3Assistant Professor of Obstetrics and Gynecology Woman’s Health Hospital Assiut University, Assiut, Egypt.
Abstract
Abstract
Objective: To identify the rate and the predictors of amenorrhea related to 1-year use of etonogestrel implant (ESI).  
Material and methods: It was a single-center; longitudinal study conducted at The Dairut Central Hospital, Assiut, Egypt from 1st of October 2021 to August 2023 included women who requested ESI for pregnancy prevention for at least 1 year. The rate of amenorrhea associated with 1-year use of ESI was reported. The changes of body mass index (BMI), the uterine and ovarian volume as well as the uterine blood flow during ESI use were also documented. Finally; the predictors associated with amenorrhea were also explored. The data were analyzed by Independent sample t-test, means of non-parametric tests and Chi-square test. Multivariate logistic regression was conducted to test for the predictors.
Results: Three hundred women were included in the study. The rate of amenorrhea at 1-year use of ESI was 38.6%. The predictive model found that fewer bleeding days, the shorter cycle, smaller uterine and ovarian volume, and higher uterine artery pulsatility index were significant predictors for amenorrhea at 1-year of ESI use. 
Conclusion: The ENG implant users have a significant rate of amenorrhea at 1-yer use. A significant increase in the BMI, decreases in the uterine and ovarian volume and the uterine blood flow were also observed. The woman should be counseled for the revealed predictors to increase the continuation and satisfaction rate. 

Keywords
Key words: Amenorrhea; Etonogestrel Implant; Implanon; Progesterone only methods.  
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