Assessment of Serum-Ascites Vitamin D Gradient (SADG) in Spontaneous Bacterial Peritonitis
El Shewi, M., Korani, S., Sabry, O., Abdou Awad, S. (2025). Assessment of Serum-Ascites Vitamin D Gradient (SADG) in Spontaneous Bacterial Peritonitis. EKB Journal Management System, 42(1), 56-67. doi: 10.21608/bmfj.2024.295275.2096
Mohammed El Sayed El Shewi; Sayed Korani; Omar Sabry; Sabry Anis Abdou Awad. "Assessment of Serum-Ascites Vitamin D Gradient (SADG) in Spontaneous Bacterial Peritonitis". EKB Journal Management System, 42, 1, 2025, 56-67. doi: 10.21608/bmfj.2024.295275.2096
El Shewi, M., Korani, S., Sabry, O., Abdou Awad, S. (2025). 'Assessment of Serum-Ascites Vitamin D Gradient (SADG) in Spontaneous Bacterial Peritonitis', EKB Journal Management System, 42(1), pp. 56-67. doi: 10.21608/bmfj.2024.295275.2096
El Shewi, M., Korani, S., Sabry, O., Abdou Awad, S. Assessment of Serum-Ascites Vitamin D Gradient (SADG) in Spontaneous Bacterial Peritonitis. EKB Journal Management System, 2025; 42(1): 56-67. doi: 10.21608/bmfj.2024.295275.2096

Assessment of Serum-Ascites Vitamin D Gradient (SADG) in Spontaneous Bacterial Peritonitis

Benha Medical Journal
Article 6, Volume 42, Issue 1, January 2025, Page 56-67  XML PDF (604.32 K)
Document Type: Original Article
DOI: 10.21608/bmfj.2024.295275.2096
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Authors
Mohammed El Sayed El Shewi1; Sayed Korani email 2; Omar Sabry3; Sabry Anis Abdou Awad4
1Professor of Gastroenterology, Hepatology and Infectious Disease - Faculty of Medicine - Benha University
2M.B.B, Ch cairo university
3Haematology department, Theodor Bilharz Research Institute (TBRI), giza, Egypt
4Professor of Gastroenterology, Hepatology and Infectious Disease - Faculty of Medicine - Benha University
Abstract
Aim and background: Spontaneous bacterial peritonitis (SBP) is an infection of the ascetic fluid that occurs in the setting of decompensated liver cirrhosis. Ascetic fluid PMN count 250 per cubic mm or above is the gold standard for it's diagnosis. The aim of this work was to assess the serum ascetic vitamin D gradient (SADG) in the setting of SBP. Methods: This cross-sectional case control analytic study was carried out on 50 patients diagnosed with portal hypertensive ascites who was categorized into two equal groups: Group I: cirrhotic ascetic patients with SBP and Group II: cirrhotic ascetic patients without SBP. Results: There was a significant positive correlation between SADG and ascetic PNM count and serum vitamin D in group I and between SADG and ascetic and serum vitamin D in group II. SADG can be used to discriminate between group I and group II at a cutoff level of < 0.55, with 72% sensitivity, 76% specificity, 75% PPV and 73.1% NPV. Ascetic fluid glucose and lactate dehydrogenase was statistically significantly higher in group II when compared with group I (P
Keywords
Serum-Ascites Vitamin D Gradient; Spontaneous Bacterial Peritonitis; Liver Cirrhosis
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