Evaluation of microRNA-9 expression levels in Iraqi women patients with breast cancer | ||||
| Journal of Bioscience and Applied Research | ||||
| Volume 10, Issue 3, September 2024, Page 421-426 PDF (1.11 MB) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/jbaar.2024.378590 | ||||
 View on SCiNiTO | ||||
| Author | ||||
Ihab Q. Ali 
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| Ibn Sina University of Medical and Pharmaceutical Sciences, Baghdad, Iraq | ||||
| Abstract | ||||
| More information about the mechanisms underlying the pathophysiology of breast cancer (BC) is needed given the widespread epidemic of the disease and its detrimental effects on women's health. The relevance of microRNAs, also known as miRNAs or miRs, for breast cancer research, has lately become known due to the extensive number of risk agents connected to this cancer. The purpose of this study was to investigate whether microRNA-9 molecules expressed as early prognostic biomarkers for breast cancer detection. Twenty-five serum samples were obtained from women who had just been diagnosed with BC, and 25 serum samples were obtained from healthy women. On the other hand, qPCR was used to look at the expression of miR-9 in study groups. The miR-9 results revealed that serum BC patients had significantly higher (P<0.05) expression when compared to controls, with fold changes of 2.8 and 1.2, respectively. | ||||
| Keywords | ||||
| Breast cancer; Real Time-PCR; miR-9 | ||||
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